Functional magnetic resonance imaging (fMRI) permits noninvasive imaging of the "human brain at work" under physiological conditions. This is the first textbook on clinical fMRI. It is devoted to preoperative fMRI in patients with brain tumors and epilepsies, which are the most well-established clinical applications. By localizing and lateralizing specific brain functions, as well as epileptogenic zones, fMRI facilitates the selection of a safe treatment and the planning and performance of function-preserving neurosurgery. State of the art fMRI procedures are presented, with detailed consideration of the physiological and methodological background, imaging and data processing, normal and pathological findings, diagnostic possibilities and limitations, and other related techniques. All chapters are written by recognized experts in their fields, and the book is designed to be of value to beginners, trained clinicians and experts alike.

Inhalt

Introduction (Background, Physiological Basics).- Methods, Data Acquisition and Processing.- Functional Neuroanatomy (Motor, Somatosensory, Language).- Presurgical fMRI in Brain Tumors (Protocols and Clinical Application).- Presurgical Functional Neuroimaging in Epilepsy.- Functional Neuronavigation.- Validity of Presurgical Functional Localization, Possibilities, Limits.- Multimodality Functional Neuroimaging.- Plasticity and Reorganization.- Pitfalls, Tips and Tricks.- Subject Index.- List of Contributors.