Based on the 75th Fujihara Seminar held in December 2018 in Tokyo, Japan, this volume explores the latest research on the cerebellum. Contributors seek to examine the cerebellum's role as a unique hub for brain activity and discover new information about its purpose. The discussion is broad, ranging from evolutionary topics to therapeutic strategy and addresses both physiology and pathology. Subjects covered include anatomy, information processing, complex spikes, plasticity, modeling, and spinocerebellar ataxias. The volume is intended to set the stage for the future of cerebellar research and guide both basic and clinical researchers.

Broad discussion of the cerebellum's role Subjects range from evolution to clinical therapies Seeks to lay out the groundwork for future cerebellar research

Autorentext

Prof. Mizusawa has been the President and now is President Emeritus of the National Center of Neurology and Psychiatry (NCNP). He works in the fields of Neurology, Neuropathology and Neurogenetics. The main foci of his current research are on therapeutics of spinocerebellar degeneration and the development of evaluation systems for cerebellar functions. He leads several international and national research programs for Neurology and Neuroscience. He, the President of the Japanese Society of Cerebellum and its Disorders, has been a Professor Emeritus of Tokyo Medical and Dental University and an editor of many journals, books, and special issues. Dr. Kakei ------ a Chief Research Scientist and Professor, works in the field of experimental and clinical Neurophysiology. The primary focus of his current research is on the cerebellar contribution to state prediction for both motor and cognitive functions. He has proposed a hypothesis that the cerebellum works as a unique CNS hub to provide a compressed prediction of the external and internal world. ------ is an editor of a journal.

Inhalt

1. Evolution and Development of the Cerebellum

2. Anatomy, Connections and Neuroimaging of the Cerebellum

3. Neurotransmission and Information Processing in the Cerebellum

4. Cerebellar Loops

5. Complex Spikes

6. Cerebellar Plasticity

7. Models of Cerebellar Functions

8. Cerebellar Disorders and their Evaluation

9. Mechanisms and Models of spinocerebellar ataxia

10. New Treatments for spinocerebellar ataxia

Conference Participants:

Timothy J. Ebner (U.S.A.), Hiroaki Gomi (Japan), Michael Häusser (UK), Germund Hesslow (Sweden), Hirokazu Hirai (Japan), Tomoo Hirano (Japan), Yutaka Hirata (Japan), Moritoshi Hirono (Japan), Takeru Honda (Japan), Kinya Ishikawa (Japan), Takahiro Ishikawa (Japan), Shinji Kakei (Japan), Yoshinobu Kano (Japan), Shigeru Kitazawa (Japan), Sheng-Han Kuo (U.S.A.), Phil Hyu Lee (Korea), Stephen G. Lisberger (U.S.A.), Mario Manto (Belgium), Javier F. Medina (U.S.A.), R. Chris Miall (UK), Takayuki Michikawa (Japan), Hiroshi Mitoma (Japan), Hidehiro Mizusawa (Japan), Keiko Muguruma (Japan), Yasunori Murakami (Japan), Yoshitaka Nagai (Japan), Soichi Nagao (Japan), Hitoshi Okazawa (Japan), Osamu Onodera (Japan), Christopher E. Pearson (Canada), Stefan Pulst (U.S.A.), Jennifer L Raymond (U.S.A.), Jeremy D. Schmahmann (U.S.A.), Reza Shadmehr (U.S.A.), Yoshikazu Shinoda (Japan), John I. Simpson (U.S.A.), Hajime Sobue (Japan), Bing-Wen Soong (Taiwan), Catherine J. Stoodley (U.S.A.), Peter L. Strick (U.S.A.), Izumi Sugihara (Japan), Mayu Takahashi (Japan), Masaki Tanaka (Japan), Peter Thier (Germany), Dagmar Timmann (Germany), Jan Voogd (The Netherlands), Kazuhiko Yamaguchi (Japan), Naoyuki Yamamoto (Japan), Tadashi Yamazaki (Japan), Michisuke Yuzaki (Japan), Chris I. De Zeeuw (The Netherlands)