Animal cells have been used in a wide range of applications, from pharmaceuticals to regenerative medicine and cell therapy, as well as evaluating drugs and compounds. These applications are supported by cell processing technology, which refers to the process technology and quality control technology for aseptically culturing cells such as skin, cartilage, and bone cells in vitro and producing the result of cells or tissues.

Cell Processing Technology provides the state of the art of cell-processing engineering, including new issues of efficient and automated culture technology of cells in transplantation and non-invasive cell quality assessment technology. The book will be of value to students and inexperienced engineers who are involved in drug discovery and cell medicine.

Explains the state-of-the-art of cell-processing engineering Focuses on the cutting-edge research and development of cell processing and related technologies that have not yet been generalized Avoids "dry experiment" element represented by computer simulations (computational methods, bioinformatics, systems biology), and limits itself to "wet experiment" related content that will lead to practical technology

Autorentext

Yuji MorimotoDepartment of Physiology, National Defense Medical College, Japan
Taka Nakahara Department of Developmental and Regenerative Dentistry, The Nippon Dental University School of Life Dentistry at Tokyo, Japan

Inhalt

1 Latest technological trends in cell processing.- 2 Evaluation of cellular dynamics in a living mouse by fluorescence imaging.- 3 Label-free & Damage-less Cell Sorting System Using Dielectrophoresis.- 4 Toxicological assessment of drugs based on electrical activities of human iPSC-derived cortical neurons, sensory neurons and cerebral organoids.- 5 Polysaccharide-based Cell Scaffolds for Cartilage Regeneration.- 6 Patient-derived stem cell medicine: a safe and reliable cell processing and regenerative therapeutic application of human dental pulp stem cells.- 7 Reconstruction of three-dimensional tissues using a tissue engineering approach involving an apatite-fibre scaffold and radial-flow bioreactor.- 8 Organ regeneration: progress in organoids and the challenges of exploiting animal developmental niches.- 9 Morphology-based non-invasive cell quality evaluation of cellular products in regenerative medicine.- 10 Control of Cell Function by Photobiomodulation.