Provides latest insights into the ovary from basic to clinical aspects Reveals recent findings on ovarian-related cells

Enriches understanding of stem cell biology of the ovary

Autorentext
Dr. Hidetaka Katabuchi, Professor and Chairman,

Department of Obstetrics and Gynecology,

Faculty of Life Sciences,

Kumamoto University

Dr. Takashi Ohba,

Associate Professor,

Department of Obstetrics and Gynecology,

Faculty of Life Sciences,

Kumamoto University

Dr. Takeshi Motohara,

Assistant Professor,

Department of Obstetrics and Gynecology,

Faculty of Life Sciences,

Kumamoto University

Klappentext

Provides latest insights into the ovary from basic to clinical aspects Reveals recent findings on ovarian-related cells Enriches understanding of stem cell biology of the ovary

Inhalt
Part I. Development of ovary; 1. Reconstitution of human germ cell development in vitro.- 2. Regulation of steroidogenesis in gonads by Ad4BP/SF-1.- 3. Role of Hedgehog-BMP4 signaling in gonadogenesis.- Part II. Ovarian stem cells and cancer stem cells; 4. Role of Lgr5-expressing stem cells in epithelial renewal and cancer in reproductive tract.- 5. Characteristics of ovarian cancer stem cells.- 6. Role of CD44 variant 6 in ovarian cancer stem cells.- Part III. Strategies for fertility preservation; 7. Rescue from primary ovarian insufficiency.- 8. Ovarian tissue cryopreservation and transplantation.- 9. Clinical management of primary ovarian insufficiency.- Part IV. Molecular and clinical aspects of epithelial ovarian cancer; 10. Molecular pathogenesis of epithelial ovarian cancer.- 11. Clinical management of epithelial ovarian cancer.- 12. Molecular targeted therapy for epithelial ovarian cancer.