The first of two companion books addressed the biology and clinical aspects of ovarian cancer. The companion title, Ovarian Cancer: Molecular & Diagnostic Imaging and Treatment Strategies, discussed both classic and the most recent imaging approaches for detection, early diagnosis and treatment of ovarian cancer. This volume, Cell & Molecular Biology of Ovarian Cancer, covers classic and modern cell and molecular biology as well as genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis, progression to metastasis, and treatment strategies including clinical trials related to ovarian cancer. Taken together, these two volumes form one comprehensive and invaluable contribution to the literature.The first of two companion books addressed the biology and clinical aspects of ovarian cancer. The companion title, Ovarian Cancer: Molecular & Diagnostic Imaging and Treatment Strategies, discussed both classic and the most recent imaging approaches for detection, early diagnosis and treatment of ovarian cancer. This volume, Cell & Molecular Biology of Ovarian Cancer, covers classic and modern cell and molecular biology as well as genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis, progression to metastasis, and treatment strategies including clinical trials related to ovarian cancer. Taken together, these two volumes form one comprehensive and invaluable contribution to the literature.

Highlights recent advances in genetics, epigenetics, and cell and molecular biology of ovarian cancer Cutting edge new information is balanced with background information readily understandable for the newcomer and the experienced ovarian cancer researcher alike Unique approach fills a gap in the literature; there are currently no recent comparable and competitive books of this sort

Autorentext

Dr. Heide Schatten is a cell and molecular biologist at the University of Missouri-Columbia. She specializes in reproduction and cancers of the reproductive systems. She has been involved as scientist adviser to advocates of Cancer Foundations and as a reviewer and study section leader of several Foundations and she has been a reviewer for the DOD prostate cancer program. She has had Cancer Research support and interacted with a large number of well-known cancer researchers including many from NIH Comprehensive Cancer Centers. Her publication record shows over 280 original publications and numerous review papers, many of which are focused on cell cycle and cytoskeletal abnormalities that are hallmarks for cancers including ovarian cancer. She has edited 19 previous books including (2013) Cell and Molecular Biology of Breast Cancer which has over 19,000 downloads.

Klappentext

The first of two companion books addressed the biology and clinical aspects of ovarian cancer. The companion title, Ovarian Cancer: Molecular & Diagnostic Imaging and Treatment Strategies, discussed both classic and the most recent imaging approaches for detection, early diagnosis and treatment of ovarian cancer. This volume, Cell & Molecular Biology of Ovarian Cancer, covers classic and modern cell and molecular biology as well as genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis, progression to metastasis, and treatment strategies including clinical trials related to ovarian cancer. Taken together, these two volumes form one comprehensive and invaluable contribution to the literature.The first of two companion books addressed the biology and clinical aspects of ovarian cancer. The companion title, Ovarian Cancer: Molecular & Diagnostic Imaging and Treatment Strategies, discussed both classic and the most recent imaging approaches for detection, early diagnosis and treatment of ovarian cancer. This volume, Cell & Molecular Biology of Ovarian Cancer, covers classic and modern cell and molecular biology as well as genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis, progression to metastasis, and treatment strategies including clinical trials related to ovarian cancer. Taken together, these two volumes form one comprehensive and invaluable contribution to the literature.

Inhalt

Microtubule-targeting agents: disruption of the cellular cytoskeleton as a backbone of ovarian cancer therapy.- Tubulin complexity in cancer and metastasis.- The impact of centrosome pathologies on ovarian cancer development and progression with a focus on centrosomes as therapeutic target.- Drug-resistant epithelial ovarian cancer: current and future perspectives.- The role of the human microbiome in epithelial ovarian cancer.- Insights into the microbial composition of intratumoral, reproductive tract, and gut microbiota in ovarian cancer patients.- The impact of mitochondria in ovarian cancer cell metabolism, proliferation, and metastasis.