This book is based on invited presentations at the Ninth International Catecholamine Symposiwn. Over several decades, each International Catecholamine Symposiwn (ICS) has provided a uniquely important forwn for updating basic as well as clinical research on the catecholamines, dopamine, norepinephrine, and epinephrine. The first ICS took nd n1 place in Bethesda, Maryland, in the USA in 1958; the 2 in Milan, Italy in 1965; the 3 th in Strasbourg, France in 1973; the 4th in Asilomar, California, USA in 1978; the 5 in th th Goteborg, Sweden in 1983; the 6 in Jerusalem, Israel,in 1987; the 7 in Amsterdam, th Netherlands in 1992; and the 8 in Asilomar, California, USA in 1996. th The 9 International Catecholamine Symposiwn (9ICS) was held in Kyoto, Japan, th March 31-April 5, 2001. This ICS was held concurrently with the 5 International th Conference on Progress in Alzheimer's and Parkinson's Disease (5 ADPD). These international meetings were coordinated to be a joint international congress. Catecholamines and related neurotransmitters and neuromediators play important roles in the pathogenesis of symptoms and neurodegenerative processes of Alzheimer's disease and Parkinson's disease. Therefore, the Joint Congress provided an opportunity for investigators and clinicians working in these fields to exchange their· most recent investigational results and clinical experiences. This Joint International Congress turned out to be an enormous success, attended by 1258 participants from 38 countries, in an enthusiastic and pleasant atmosphere.

Inhalt
In Memorium.- Dr. Sidney Udenfriend Memorial Lecture.- Catecholamine Uptake, Storage, and Release.- Regulation of Catecholamine Biosynthetic Enzymes.- The Dopaminergic System.- Developmental Neurobiology of Catecholaminergic Systems.- Physiological Effects of Catecholamines.- Methodological Advances.- Catecholamines Stress and Behavior.- Catecholamines and Drugs of Abuse.- Involvement of Catecholamines in Clinical Medicine.- 99. Dopamine Receptors in Schizophrenia.- 100. The Dopamine Hypothesis of Schizophrenia: New Aspects.- 101. Molecular Genetic Analysis of Plasma Dopamine ?-Hydroxylase in Depression: New Implications for An Old Biomarker.- 102. Dopaminergic Hyperactivity in Striatum in Schizophrenia: A Failure of Cortical Glutamatergic Control?.- 103. Tetrahydrobiopterin Differentially Regulates the Biosynthesis of Catecholamines and Serotonin: Implication in Neuropsychiatric Disorders.- 104. Lithium and Signal Transduction.- 105. Platelet Monoamine Oxidase, Transcription Factor AP-2 and PersonalityA Functional Triangle?.- 106. Cardiac Sympathetic Denervation in Parkinson's Disease.- 107. Dopaminergic Impairment Is Related to Cortical Dysfunction in Parkinson's Disease: A PET Study.- 108. Aliphatic Propargylamines as Treatments for Neurodegenerative Diseases: Catecholamine ResearchFrom Molecular insights to Clinical Medicine.- 109. ß-Carbolines and N-Methylation Underlying Parkinson's Disease.- 110. Neuroprotective Actions of Green Tea Polyphenol, (-)-Epigallocatechin-3-Gallate in Models of Parkinson's Disease: Gene Targets.- 111. Dopamine Transporter and Parkinson's Disease.- 112. L-Dopa Responsive Dystonia/Infantile Parkinsonism Associated with Mutations at the Human Tyrosine Hydroxylase Locus.- 113. Dopamine Is a Pathogenetic Factor inHIV-Induced Neuro-AIDS.- 114. Models of Parkinson's Disease.- 115. The Effect of Acute Loading with Selegiline and Selegiline with Levodopa on Blood Pressure and Plasma Norepinephrine Levels in Chronic Parkinsonian Patients.- 116. Cardiac Sympathetic Imaging with Radiolabelled Metaiodobenzylguanidine (MIBG) in Patients with Parkinson's Disease.- 117. MIBG Scintigraphy in Parkinsonian Syndromes.- 118. Evaluation of Sympathetic Nerve Function in Patients with Heart Failure by MIBG Myocardial Scintigraphy.- 119. Familial Orthostatic Tachycardia due to Norepinephrine Transporter (SLC6A2) Deficiency.- 120. Sympathetic Innervation and Blood Flow in the Diabetec Heart.- 121. Dynamic Monitoring of Neurological Diseases by CSF Clinical Markers.- 122. Comparative Physiology and Morphology of Catecholamine Systems: Beta Adrenergic Receptor-Mediated Attenuation of TNF?-Stimulated ICAM-1 Expression on Human Brain Microvascular Endothelial Cells.- 123. Cloning of Novel Genes from the Human Spinal Cord by Molecular Profiling.- 124. Molecular Biology of Conformational Diseases.- 125. An Approach to Establish Antemortem Diagnosis of Dementia with Lewy Bodies.- 126. Sympathoadrenal Activity and Cardiovascular Responses during Space Flight.- 127. Estrogen Metabolism: Does the Formation of Estrogen Quinone Provide a Potential Pathway to Breast Carcinogenesis?.