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Cardiovascular Genetics and Genomics for the Cardiologist

  • Fester Einband
  • 328 Seiten
Promises to remodel the way cardiovascular medicine is practised * Written and edited by two pioneers in this area * Specially sel... Weiterlesen
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Promises to remodel the way cardiovascular medicine is practised * Written and edited by two pioneers in this area * Specially selected material for the practising clinician * Must-have reference to this developing field to ensure up-to-date patient care .


Victor J. Dzau, MD James B. Duke Professor of Medicine, Director, Mandel Center for Hypertension and Atherosclerosis Research; and Chancellor for Health Affairs, Duke University, Durham, USA Choong-Chin Liew, PhD Professor Emeritus, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; and (formerly) Visiting Professor of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA


Genes and genomes will become very important to the cardiologist in the very near future. This textbook will introduce the cardiologist and cardiovascular investigator to the concepts of cardiovascular genetics and genomics - a field that did not exist twenty years ago and that now promises to remodel the way that cardiovascular medicine is practiced. Written and edited by two of the pioneers in this area, this text will provide a clinically integrated presentation, which will be of interest to all cardiologists and internists who must know this material in order to provide up-to-date patient care.


Contributors.Foreword.Introduction.1 The gene in the twenty-first century.Choong-Chin Liew, Victor J. Dzau.Part I: Cardiovascular single gene disorders.2 Monogenic hypercholesterolemia.Ruth McPherson.3 Hypertrophic cardiomyopathy.Ali J. Marian.4 Dilated cardiomyopathy and other cardiomyopathies.Mitra Esfandiarei, Robert Yanagawa, Bruce M. McManus.5 The long QT syndrome.Sabina Kupershmidt, Kamilla Kelemen, Tadashi Nakajima.Part II: Cardiovascular polygenic disorders.6 Atherosclerosis.Paivi Pajukanta, Kiat Tsong Tan, Choong-Chin Liew.7 Heart failure.Markus Meyer, Peter VanBuren.8 The implications of genes on the pathogenesis, diagnosis and therapeutics of hypertension.Kiat Tsong Tan, Choong-Chin Liew.Part III: Therapies and applications.9 Gene therapy for cardiovascular disease: inserting new genes, regulating the expression of native genes, and correcting genetic defects.Ion S. Jovin, Frank J. Giordano.10 Stem cell therapy for cardiovascular disease.Emerson C. Perin, Guilherme V. Silva.11 Pharmacogenetics and personalized medicine.Julie A. Johnson, Issam Zineh.12 The potential of blood-based gene profiling for disease assessment.Steve Mohr, Choong-Chin Liew.Index.Colour plates


Titel: Cardiovascular Genetics and Genomics for the Cardiologist
EAN: 9781405133944
ISBN: 978-1-4051-3394-4
Format: Fester Einband
Herausgeber: John Wiley and Sons Ltd
Genre: Medizin
Anzahl Seiten: 328
Gewicht: 928g
Größe: H263mm x B187mm x T21mm
Jahr: 2007