Klappentext Caenorhabditis elegans has been a popular model organism for biological research for over thirty years with a dramatic increase in interest since the publication of the entire genome sequence in 1998. It is currently the only multicellular animal to have its entire genome sequenced. This Practical Approach book provides all the essential background information required for use of C. elegans as a model system and includes information on how to usethe genome sequence information. Zusammenfassung Gives all the basic information on C. elegans required to use it, including details on how to obtain, grow, and maintain C. elegans for use as a model system. Chapters also describe the genome project, provide practical details of transformation and describe strategies for gene inactivation. Inhaltsverzeichnis Preface; 1. Hope: Background on Caenorhabditis elegans; 2. Blaxter: The Genome Project and Sequence Homology to Other Species; 3. Thierry-Mieg: C. elegans and the Web; 4. Stiernagle: Maintenance of C. elegans; 5. Jin: Transformation; 6. Barstead; Reverse Genetics; 7. Schnabel: Microscopy; 8. Thomas: Neurobiology; 9. Mounsey: Gene Expression Patterns; 10. Johnstone: Molecular Biology; 11. McGhee: Biochemistry of C. elegans; 12. Hodgkin: Conventional Genetics; Index

Inhalt
Preface; 1. Hope: Background on Caenorhabditis elegans; 2. Blaxter: The Genome Project and Sequence Homology to Other Species; 3. Thierry-Mieg: C. elegans and the Web; 4. Stiernagle: Maintenance of C. elegans; 5. Jin: Transformation; 6. Barstead; Reverse Genetics; 7. Schnabel: Microscopy; 8. Thomas: Neurobiology; 9. Mounsey: Gene Expression Patterns; 10. Johnstone: Molecular Biology; 11. McGhee: Biochemistry of C. elegans; 12. Hodgkin: Conventional Genetics; Index