Bioanalysis and Biosensors for Bioprocess Monitoring

This special volume on "bioanalysis and biosensors for bioprocess monitoring" has a twofold target. Firstly, it is dedicated to the 75th birthday ofArmin Fiechter, who was a major driving force among the pioneers to the progress of biochemical engineering. Not only the aseptic connection technique with septa and needles still used until today was established by him, but also the development of the first sterilizable pH electrodes with W Ingold is also credited to him. He made in vivo bio analysis a topic of general interest, for instance by setting up the first chemostat in Switzerland. It was again Armin Fiechter who pushed the use of non invasive exhaust gas analysis in the late 1960s and promoted development and exploita tion of in situ sensors and on line analytical instruments in bioprocessing, among other means, by founding a spin off company. In his laudatio, Karl Schtigerl extends the list of his merits and achievements.

This review series covers trends in modern biology. All aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computerscience, are treated. In parts of the series special volumes are dedicated to selected topics. Includes supplementary material: sn.pub/extras

Inhalt
Instrumentation of Biotechnological Processes.- Electronic Noses for Bioreactor Monitoring.- Rapid Analysis of High-Dimensional Bioprocesses Using Multivariate Spectroscopies and Advanced Chemometrics.- On-line and Off-line Monitoring of the Production of Cephalosporin C by Acremonium chrysogenum.- Biomass Quantification by Image Analysis.- Monitoring the Physiological Status in Bioprocesses on the Cellular Level.- Metabolic Network Analysis.