In this volume there is a strong emphasis on translational science, with preclinical approaches suggesting new directions for development of new treatments. Individual chapters describe how neuroimaging, neuroendocrine, genetic and behavioral studies use powerful research tools that are offering a completely new understanding of the factors that increase vulnerability to ADHD. The clinical impact of co-morbid problems, especially obesity and substance misuse, are highlighted and explain what such problems can tell us about the etiology of ADHD, more generally. Reviews of the pharmacology of established drug treatments for ADHD justify an exciting novel theory for their therapeutic actions and address questions about the effects of their longterm use.

A rich compendium that pulls together evidence from the basic and clinical neurosciences to provide an update on characteristics, comorbidity, potential causes , consequences and treatment of ADHD Strong emphasis on translational research of ADHD, leading from science to evidence-based novel treatment and coping strategies Offers a new paradigm for understanding ADHD Contributing authors are international basic and clinical researchers Includes supplementary material: sn.pub/extras

Klappentext

The Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder reviews the latest discoveries in research of ADHD. There is a strong emphasis on translational science, with preclinical approaches suggesting new directions for development of new treatments. Individual chapters describe how neuroimaging, neuroendocrine, genetic and behavioral studies use powerful research tools that are offering a completely new understanding of the factors that increase vulnerability to ADHD. The clinical impact of co-morbid problems, especially obesity and substance misuse, are highlighted and explain what such problems can tell us about the etiology of ADHD, more generally. Reviews of the pharmacology of established drug treatments for ADHD justify an exciting novel theory for their therapeutic actions and address questions about the effects of their longterm use. This volume is aimed at both clinicians and basic scientists, who are interested in ADHD, giving students and established researchers an overview of the current status of the field and insight into topics that will be prominent in the future.

Inhalt

From the contents: ADHD in children and adults: diagnosis and prognosis.- ADHD: Volumetry, Motor, and Oculomotor Functions.- Neurodevelopmental abnormalities in ADHD.- Intra-individual Variability in ADHD and its Implications for Research of Causal Links.- Hypothalamic pituitary - adrenocortical function in Attention Deficit / Hyperactivity Disorder.- Brain Processes in Discounting: Consequences of Adolescent Methylphenidate Exposure.- Attention Deficit Hyperactivity Disorder and Substance Use Disorders.- Linking ADHD, impulsivity and drug abuse: a neuropsychological perspective.- Obesity and ADHD: clinical and neurobiological implications.- Face Processing in Attention Deficit/Hyperactivity Disorder.- Quantitative and molecular genetics of ADHD.- Rodent models of ADHD.- Rat Models of ADHD.- Epigenetics: Genetics versus Life Experiences.- Sexual differentiation of the brain and ADHD: What is a sex difference in prevalence telling us?- ADHD: Current and future therapeutics.- The Four Causes of ADHD: A Framework.