Due to the high prevalence of polypharmacy in older adults, there is a growing interest among healthcare facilities and practitioners to perform pharmacogenomic testing in this population. However, the complexity of multimorbidity and polypharmacy, the physiologic changes of aging, and the lack of direct clinical guidance in this area may cause clinicians to struggle with how to utilize pharmacogenomic test results safely and effectively to guide clinical care.

Applying Pharmacogenomics to Optimize Geriatric Care aims to fill this gap by briefly reviewing the foundational science behind each of these complicated factors, how to converge clinical factors with genetic testing, and how to clinically act on pharmacogenomic test panel results. Taken together, this book is a deep dive into applying foundational sciences to establish a framework for approaching complex situations in older adults. It systematically works through case examples of frequently encountered complex patient situations, providing clinicians with practical examples and evidence-based guidance on how to integrate pharmacogenomics with clinical factors to provide personalized patient care in various complex situations.

Seeks to meet the growing interest in pharmacogenomic applications across multiple organ systems Focuses on geriatric patients, including the complexity of multimorbidity and polypharmacy in this population Presented in a case-based format with reviews of the foundational science of pharmacogenomics and tips for each case

Autorentext

Teresa DeLellis, PharmD, BCPS, BCGP, AGSF

Chair, Department of Pharmacy Practice
Associate Professor of Pharmacy Practice
Transitions of Care/Geriatric Clinical Specialist
Manchester University, College of Health Professions, Nursing & Pharmacy

Yee Ming Lee, PharmD, BCPS, ABCP

Associate Professor, Department of Clinical Pharmacy
University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences

David Bright, PharmD, MBA, FAPhA, FCCP

Professor, Department of Pharmaceutical Sciences

Ferris State University College of Pharmacy

Youssef Roman, PharmD, PhD

1- Associate Professor of Pharmacy Practice and Administrative Sciences
L. S. Skaggs College of Pharmacy, Idaho State University
2- Pharmacy Specialist at Boise Veterans Affairs Medical Center
Boise, Idaho

Stephanie L. Sibicky, PharmD, MEd, BCGP, BCPS, FASCP
Clinical Professor, Department of Pharmacy and Health Systems Sciences
Assistant Dean for Academic Affairs and Assessment
Northeastern University School of Pharmacy and Pharmaceutical Sciences

Inhalt

Section 1: Foundation .- Physiologic Effects of Aging, Multimorbidity, and Polypharmacy on Care Outcomes.- Introduction to Pharmacogenomics.- Integrating Pharmacogenomics into Geriatric Care: Challenges and Opportunities.- Section 2: Application.- Pharmacogenomics and Pain Control for Older Adults.- Pharmacogenomics and Gastrointestinal Care in Older Adults.- Pharmacogenomics and Cardiovascular Care for Older Adults.- Pharmacogenomics and Psychiatry Care for Older Adults.- Pharmacogenomics and Central Nervous System Care for Older Adults.- Bringing it All Together.