Anabolic-Androgenic Steroids

This volume was planned to provide a comprehensive survey of the role of the anabolic-androgenic steroids in the vital economy exclusive of the androgenic (sexual) functions. It seemed appropriate to bring together all of this information in an organized fashion in one volume at this time not only to serve as a source of information but also to indicate and suggest areas that need further exploration. The anabolic action of the steroid hormones has gone through a period of great activity in both basic and clinical research. A complete understanding of the manifold anabolic effects still remains to be elucidated and the art of clinical application is only gradually becoming apparent. This volume should be useful not only to the experienced investigator in both basic and clinical research but also for the novice. Furthermore, it should serve as a source of information for the careful use of these steroids in certain metabolic diseases. These steroids have had wide clinical application with variable results. In many instances further careful exploration is suggested. Other instances have demonstrated varying degrees of usefulness.

Inhalt
I. Historical Review of Anabolic-Androgenic Steroids..- References.- II. Metabolic Effects.- A. Metabolic Effects of Anabolic-Androgenic Steroids in Experimental Animals..- B. The Metabolic Effects of Anabolic Steroids in Man..- III. Sites of Tissue Formation.- A. Body and Organ Weights and Composition..- B. Effect of Anabolic-Androgenic Steroids on the Skin, Including Hair and Sebaceous Glands..- C. Anabolic-Androgenic Steroids and Experimental Mammary Tumors..- IV. Mechanism of Action.- A. Regulation of Protein Synthesis by Anabolic-Androgenic Steroids..- B. Regulation of Nucleic Acid Synthesis by Anabolic-Androgenic Steroids..- C. Regulation of Tissue Enzymes..- D. The Metabolism in Vitro of Anabolic-Androgenic Steroids by Mammalian Tissues..- V. Dissociation of the Androgenic and Other Hormonal Activities from the Protein Anabolic Effects of Steroids..- VI. Animal Husbandry..- VII. Clinical Applications.- A. Effect of Androgens on Bone, Calcium, and Phosphorus Metabolism..- B. The Use of Anabolic-Androgenic Steroids in Childhood and Adolescence..- C. The Hematologic Effects of Androgens.- D. Cancer in Man..- E. Athletics..- F. Miscellaneous Uses of Anabolic Steroids..- VIII. Appendix.- Author Index.- Addendum.- VII. E. Athletics, A.J. Ryan.