"A very impressive addition to the library of books and resources available for embryologists in training and in practice The combined format of the text, pictures, and the online supplements in a simple accessible format make this a great book A very useful book for trainers on and students training in clinical embryology." - (Highly Commended, Obstetrics & Gynecology, BMA Medical Book Awards 2016)

Autorentext

Edited by

Alison Campbell, M. Med. Sci, head of embryology, CARE Fertility Group, Nottingham, UK

Simon Fishel, PhD, professor of human reproduction and CEO, CARE Fertility Group, Nottingham, UK

Klappentext

Time lapse imaging of the pre-implantation embryo is a new and extremely exciting development in Reproductive Medicine, offering a clinic the potential of higher successful embryo implantation rates by revealing and interpreting hitherto unnoticed detail about the speed and timing of development. This concise handbook documents the results that are known to date and shows how use of the technique can benefit a clinic.

Zusammenfassung

Unlike conventional single daily observations, time lapse technology provides hundreds of images, which allows pinpointing of key events in the embryo's in vitro development as well as the detection of brief but significant critical changes. This information is beneficial in selecting the most viable embryos from a cohort and increases the chances of a positive outcome.

The Atlas of Time Lapse Embryology describes in detail the technology and techniques surrounding time lapse embryology. ****The book also covers the clinical aspects of time lapse imaging, morphokinetic timings, implantation data, fertilization, compaction, blastulation, irregular cleavages, multinucleation, vacuolation, zona defects, and other topics.

The book is easy to read, practical, and illustrated with dozens of images and video clips to help explain a variety of concepts. It will help practitioners to better understand how time lapse monitoring may dramatically increase flexibility in the IVF clinic, and most importantly, enhance clinical outcomes.

Print Versions of this book also include access to the ebook version.

Inhalt

Equipment Required for Time Lapse Observations in In Vitro Fertilization. Clinical Aspects of Time Lapse Imaging. Time Lapse, the Cell Cycle, Distribution of Morphokinetic Timings, and Known Implantation Data. Gender and Morphokinetics Correlation. Polar-Body Extrusion. Fertilization: Pronuclear Formation and Fading. Clinical Results: Dynamic AspectsFragmentation. Number of Pronuclei and Ploidy in IVF /ICSIDerived Embryos. Dynamic Aspects: Compaction. Blastulation. Hatching of the Human Blastocyst. Irregular Cleavages. Reverse Cleavage/Blastomere Fusion. Smooth Endoplasmic Reticulum Clusters. Multinucleation. Vacuolation. Granular Cytoplasm. Zona Defects. The Patient Perspective.