McAlpine's Multiple Sclerosis

Autorentext

Alasdair Coles, Ph.D. is a Professor of Neuroimmunology in the Division of Clinical Neurosciences at the University of Cambridge. Has been doing MS research in Cambridge since 1994. He is also a consultant neurologist. With Alastair Compston, he was very involved in the development of alemtuzumab as a treatment of MS. He is employed as a senior lecturer by Cambridge University and has a small research team managing clinical trials and doing human immunological laboratory work. He does clinical work for two days a week as a consultant neurologist at Addenbrooke's and Peterborough Hospitals, is one of the medical advisers to the Multiple Sclerosis Society of the UK, and advises several pharmaceutical companies.

Klappentext

For more than 70 years, McAlpine's Multiple Sclerosis has been the gold standard textbook on the science and clinical practice of MS. The 5th Edition of this classic, landmark text reflects recent advances ****in this complex field, bringing you up to date with current information on genetics, epidemiology, clinical neurology, pathogenesis, and management of this common neurological disease. Easy to read and abundantly illustrated, this updated reference is a must-have resource for neurologists, neuropathologists, neurophysiologists, researchers, PM&R specialists, and others who can benefit from authoritative, comprehensive coverage of both scientific and clinical aspects of MS.

• Discusses recent advances in both diagnosis and management, including improved understanding of MS in childhood and the elderly, anti-MOG disease, treatments of progressive MS, remyelination and neuroprotective therapies, and more
• Offers authoritative reviews of the current literature, placed in historical context
• Features more than 550 high-quality illustrations clarifying important scientific and clinical concepts
• Provides the most authoritative and comprehensive history of the understanding of the disease
• Uses a remarkably clear presentation to make complicated data easier to understand
• An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish after the publication date

Inhalt

1. The Concept of Multiple Sclerosis
2. The Pathogenesis and Etiology of Multiple Sclerosis
3. The Person With Multiple Sclerosis: Treatment and Society
4. Telling the Story: Literature and McAlpine’s Multiple Sclerosis
5. Distribution of Multiple Sclerosis
6. Natural History of Multiple Sclerosis
7. Diagnosis and Classification of Multiple Sclerosis
8. Symptoms and Signs
9. Imaging Structure
10. Measuring Function
11. Blood and CSF Markers of Damage and Disease Activity
12. Diagnosis and Differential Diagnosis
13. Genetic Analysis of Multiple Sclerosis
14. Immunology of Multiple Sclerosis
15. Neurobiology of Multiple Sclerosis
16. The Pathogenesis of Multiple Sclerosis: A Pandect
17. Care of the Person With Multiple Sclerosis
18. The Acute Attack of Multiple Sclerosis and Its Treatment
19. The Treatment of Symptoms in Multiple Sclerosis
20. Disease-Modifying Immunotherapies
21. Reparative Therapies
22. Monitoring Treatment