This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging interventions.

Aging has been becoming a global health problem. However it was not possible to determine aging as we usually diagnose a disease because there are few biomarkers for age estimation. Since ancient times, people have been seeking anti-aging substances and methods for achieving immortality, while the scientific study of aging has only existed for 100 years. This book appeals to researchers both in institutes and in pharmaceutical companies interested in further studies in this field.

Autorentext

Dr. Zhao Wang is a Professor at the School of Pharmaceutical Sciences, Tsinghua University, China. He is also a Project Professor at the National Okayama University, Japan. Dr. Wang is a senior member of Chinese Pharmaceutical Association and foreign member of the Pharmaceutical Society of Japan. He serves(d) as the editorial board member for numerous academic journals, such as Scientific Reports (USA), Pharmazie (Germany) and the Journal of Pharmacological Sciences (Japan). His research focuses on the mechanisms and interventions of aging. He has published more than 90 research articles in international journals in this field.

Inhalt

System Biology in Aging Research.- Circular RNA in Aging and Age-Related Diseases.- Non-Coding Rnas in Cardiovascular Aging.- Epigenetic Regulation of Vascular Aging.- Apoe and Neurodegenerative Diseases in Aging.- Brain Aging: Hsp90 and Neurodegenerative Diseases.- Aging of Human Adult Stem Cells.- Mechanisms of Hematopoietic Stem Cell Aging and Targets for Hematopoietic Tumor Prevention.- Microbiota and Aging.- Intestinal Homeostasis and Longevity: Drosophila Gut Feeling.- Aging Kidney and Aging Related Disease.- Aging of Bone.- Ovarian Aging and Osteoporosis.- Biomarkers of Human Aging.- Pharmaceutical Intervention of Aging.- Application of Stem Cell Technology in Anti-Aging and Aging Related Diseases.- Which Is Better: Meta-Analysis of Different Anti-Aging Strategies