This book constitutes the refereed proceedings of the 11th Brazilian Symposium on Bioinformatics, BSB 2018, held in Rio de Janeiro, Brazil, in October/November 2018. The 13 revised full papers presented were carefully reviewed and selected from 26 submissions. The papers cover all aspects of bioinformatics and computational biology.

Inhalt
Sorting -Permutations by -Operations.- Super Short Reversals on Both Gene Order and Intergenic Sizes.- Identifying Maximal Perfect Haplotype Blocks.- Sorting by Weighted Reversals and Transpositions.- Graph databases in Molecular Biology.- ViMT - Development of a Web-based Vivarium Management Tool.- An argumentation theory-based multiagent model to annotate proteins.- AutoModel: a client-server tool for intuitive and interactive homology modeling of protein-ligand complexes.- Detecting Acute Lymphoblastic Leukemia in Down Syndrome Patients using Convolutional Neural Networks on Preprocessed Mutated Datasets.- S 2 FS : Single score feature selection applied to the problem of distinguishing long non-coding RNAs from protein coding transcripts.- A Genetic Algorithm for Character State Live Phylogeny.- A workflow for predicting microRNAs targets via accessibility in Flavivirus genomes.- Parallel solution based on collective communication operations for phylogenetic bootstrapping in PhyML 3.0.