This book offers up-to-date and comprehensive coverage of the diagnosis and therapy of adenocarcinoma of the esophagogastric junction (EGJ). As is appropriate in the era of multidisciplinary and multimodal treatment, the contributions of all the various specialists involved cooperatively in the treatment of EGJ cancer are thoroughly described. Detailed attention is also paid to the significance of preneoplastic lesions, such as Barrett esophagus. The final part of the book represents a surgical atlas documenting the techniques used in the EGJ region, with superb color images and stepwise description of procedures. Against the background of the rapidly increasing incidence in EGJ cancer, especially evident in Western countries, there is a need for greater uniformity in management strategies, which currently vary significantly across the world. This book provides appropriate guidance that will assist all practitioners involved in the diagnosis and treatment of EGJ cancers, including surgeons, oncologists, and radiotherapists.

Offers comprehensive guidance on the diagnosis and treatment of cancer of the esophagogastric junction Emphasizes the role of multimodal treatment Reports new knowledge and innovations Discusses the significance of preneoplastic lesions

Autorentext

Simone Giacopuzzi graduated in Medicine from the University of Verona in 2002 and gained a Degree in General Surgery (70/70 and distinction) from the University of Verona in May 2008. During 2009 he spent 6 months as an observer at Fujita Health University, where he completed a training program in laparoscopic upper digestive surgery. Since 2009 he has worked as a General Surgeon in the Department of Upper GI Surgery at Verona Hospital. Since January 2013 he has also attended the PhD course at the Department of Surgery, University of Verona. He has cooperated with the Scientific Committee of the 10th IGCC (International Gastric Cancer Congress) as chairman of the web round table, Laparoscopy and robotic treatment. What is evidence based? Dr. Giacopuzzi is author or co-author of 20 indexed journal articles and co-author of a book on esophageal cancer. His research interests include surgical oncology for solid tumors, especially upper GI cancer, and minimally invasive surgery.

Andrea Zanoni graduated cum laude in Medicine from the University of Verona in 2006 and specialized cum laude in General and Emergency Surgery at the University of Verona in 2013. He was an international observer at the Department of Thoracic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA from November 2012 to April 2013 and is at present a research fellow at the Department of Upper GI Surgery at the University of Verona. He is the author of five scientific articles in international and Italian journals and co-author of a book on squamous cell carcinoma of the esophagus. Dr. Zanoni is a reviewer for an international journal on esophageal diseases and was involved, with the Scientific Committee, in the organization of the 10th IGCC, held in Verona in 2013. He was a speaker at the 12th and 13th World Congresses of the International Society for Diseases of the Esophagus.

Giovanni de Manzoni is Full Professor of Surgery and a Consultant in the Department of Surgery,University of Verona, Italy. He is President of the International Gastric Cancer Association for the years 2013-2015 and Coordinator and General Secretary of the Italian Research Group for Gastric Cancer. He is also a longstanding member of the International Gastric Cancer Association and the Advisory Board of the Brazilian Gastric Cancer Association. Dr. de Manzoni is a member of the editorial board of Gastric Cancer , official journal of the International Gastric Cancer Association. His clinical and research activity focuses on (among other topics) surgical oncology for solid tumors, extended lymphadenectomy in upper GI cancer, and tumor prognostic factors and staging. He is the author of various books and over 160 articles in PubMed-cited journals.

Inhalt

Foreword.- Preface.- 1 Epidemiology and risk factors.- 2 Barrett's esophagus: pathogenesis and prevention.- 3 Surveillance in Barrett's esophagus and Dysplasia.- 4 Ablation techniques for Barrett's esophagus and Dysplasia.- 5 Endoscopic resection for Barrett's esophagus and Dysplasia.- 6 7th Edition AJCC/UICC Staging: Esophagus and Esophagogastric Junction.- 7 Siewert Classification of Adenocarcinoma of the Esophagogastric Junction: still in or already out ?.- 8 Preoperative work- up: conventional radiology, ultrasonography, CT scan and MRI.- 9 Role of PET/CT and MRI in the prediction of response to neoadjuvant treatment.- 10 Molecular biology in the prediction of response to neoadjuvant treatment.- 11 Pathological response to neoadjuvant treatment: more questions than answers.- 12 Hospital volume and centralization in EGJ cancer.- 13 Patient selection and tailored treatment principles.- 14 How to treat EGJ cancer: indications and treatment strategy.- 15 Chemotherapy in EGJ cancer.-16 Chemoradiation in EGJ cancer.- 17 Signet ring carcinoma in EGJ: what is it?.- 18 Morbi- mortality and treatment of complications.- 19 Long term results in surgery alone and multimodal treatments.- 20 Open or minimally invasive? Comparison of early and late results.- 21 Enhanced Recovery After Surgery (ERAS and nutritional aspects.- 22 Unresectable and metastatic cancer.- 23 Recurrence: treatment or just palliation?.- 24 Follow- up and quality of life.- 25 Surgical anatomy of esophagus and esophagogastric junction.- 26 Surgical technique: open procedures.- 27 Surgical technique: minimally invasive procedures.- Subject Index.