This book presents up-to-date, practically oriented information on major topics in chronic hepatitis C. The coverage encompasses epidemiology; diagnosis, including molecular methods; treatment and challenges; and the management of co-infections. Readers will find guidance on pretherapeutic evaluation with respect to disease severity and extrahepatic manifestations. Resistance to antiviral treatment and its management are discussed, and the nature of optimal follow-up is addressed in detail. Treatment of HCV/HIV co-infection is considered separately, and the approach in special patient populations is thoroughly examined. Chronic Hepatitis C will be of high value for general practitioners and specialists in gastroenterology, infectious diseases, and internal medicine. It will be international in scope in terms of both authorship and appeal.

Autorentext

Resat Ozaras, MD, Professor is in Infectious Diseases Department of Cerrahpasa Medical School, Istanbul University, Turkey. He studies acute hepatitis and chronic hepatitis of B, C, and D. He is a member of Viral Hepatitis Study Group of European Society of Clinical Microbiology and Infectious Diseases (ESCMID).

Dominique Salmon Ceron, MD, PhD, is Professor of Infectious and Tropical Diseases at Paris Descartes University. She leads the HIV and Anti-Infective Research Group and works in the Infectious Diseases Department at Cochin Hotel Dieu Hospital in Paris. Her translational research focuses on the clinical aspects of hepatitis C and HIV co-infection and she is the chair of the national cohort of HIV/HCV-coinfected patients established in France by the French National Agency for Research on AIDS and hepatitis. She has created the European Study Group for Viral Hepatitis (ESGVH) and has served as chair of this group for several years. In France, she is actively involved in the expert groups developing recommendations for HIV and hepatitis and national vaccine policies. She has authored more than 150 peer-reviewed publications.

Inhalt

1.       Pretherapeutic evaluation of the patients and evaluation of the severity of hepatic disease

2.       HIV HCV co-infection: current challenges

3.       TREATMENT OF HEPATITIS C VIRUS INFECTED PATIENTS WITH RENAL FAILURE

4.       Global Epidemiology of Chronic Hepatitis C Virus Infection

5.       LABORATORY AND MOLECULAR DIAGNOSIS OF HEPATITIS C AND RESISTANCE TESTING

6.       EXTRAHEPATIC MANIFESTATIONS OF HEPATITIS C VIRUS INFECTION

7.       Current Therapy of Chronic Hepatitis C Virus in Treatment Naive Patients

8.       Management of Interferon-Free Direct-Acting Antiviral Therapy Failure

9.       Management of HCV Infection In Decompen-sated Cirrhosis In The Transplantation Setting

10.   Treatment of Hepatitis C Virus in Special populations (HBV co-infection, Drug users and prisoners)

11.   Acute Hepatitis C