Evidence-based medicine (EBM) stresses the use of evidence from clinical research as the basis for medical decision making, rather than simple reliance on unsystematic clinical experience and pathophysiological rationales. EBM has changed many aspects of medical practice for the better, but its incorporation into endocrine practice has been minimal. In Evidence-Based Endocrinology, internationally recognized experts, pioneers, and opinion makers in EBM provocatively recast endocrine policy and practice in the light of its philosophy and principles. The authors explain the past, present, and future of EBM; consider its practical implications for endocrinology; demonstrate what the "evidence base" is in EBM; and present illustrative case studies by practicing evidence-based clinicians. Highlights include essays on why cost-effective analyses are problematic, the contrast between clinical investigations and large randomized trials, the role of Cochrane reviews and meta-analyses, and the curriculum requirements for training evidence-based endocrinologists.
Authoritative and cutting-edge, Evidence-Based Endocrinology not only spells out the high value of EBM, but also its limitations, challenging endocrinologists to embrace its principles in the best interests of their patient practice.

Zusammenfassung
Internationally recognized experts, pioneers, and opinion makers in evidence-based medicine (EBM) provocatively recast endocrine policy and practice in the light of EBM philosophy and principles. The authors explain the past, present, and future of EBM; consider its practical implications for endocrinology; demonstrate what the "evidence base" is in EBM; and present illustrative case studies by practicing evidence-based clinicians. Highlights include essays on why cost-effective analyses are problematic, the contrast between clinical investigations and large randomized trials, the role of Cochrane reviews and meta-analyses, and the curriculum requirements for training evidence-based endocrinologists.

Inhalt
The New Endocrinologist.- The New Endocrinologist.- Past, Present, and Future.- A Short History of Evidence-Based Medicine.- The Philosophy of Evidence-Based Medicine.- Preparing Future Generations of Evidence-Based Endocrinologists.- Practicing Evidence-Based Endocrinology.- Finding Current Best Evidence in Endocrinology.- Integrating Evidence Into Clinical Diagnosis.- Supporting Evidence-Based Endocrine Practice.- Supporting Patients' Participation in Decision Making.- Incorporating Evidence Into Health Policy Decisions.- Research Evidence for Evidence-Based.- The Value of Observational Studies in Endocrinology.- Clinical Research Center-Based Investigations and Evidence-Based Medicine.- The Value of Systematic Reviews in Endocrinology.- Health-Related Quality-of-Life Assessment in Endocrinology.- Decision Analysis in Endocrinology.- Clouded Thinking.- Translation Research in Diabetes.- Case Studies in Evidence-Based Practice.- The Patient With Type 1 Diabetes and Hypoglycemia.- The Patient With Medically Complicated Obesity.- The Patient at Risk for Diabetes Considering Prevention.- An Evidence-Based Approach to Type 2 Diabetes.- Patients With Diabetes Using Alternative Medicine.- Evidence-Based Case Studies in Osteoporosis.- The Neuroendocrinology of Medically Unexplained Syndromes.