This volume constitutes the thoroughly refereed post-conference proceedings of the 10th International Conference on Verified Software: Theories, Tools, and Experiments, VSTTE 2018, held in Oxford, UK, in July 2018. The 19 full papers presented were carefully revised and selected from 24 submissions. The papers describe large-scale verification efforts that involve collaboration, theory unification, tool integration, and formalized domain knowledge as well as novel experiments and case studies evaluating verification techniques and technologies.