This third volume of "Uveitis and Immunological Disorders" in Essentials in Ophthalmology provides up-to-date, relevant information for the reader. Our knowledge and understanding of immune mechanisms has increased exponentially over the past few years and has expanded to disorders such as diabetic retinopathy and macular degeneration. This volume will provide the ophthalmologist with practical information on how to diagnose and treat these difficult, and in some cases, blinding disorders. In addition, there are important discussions of the mechanisms underlying these conditions, which incorporate the most recent, up-to-date research material available. "Summary for the Clinician" and "Core Messages" sections enhance the value of each chapter.

This volume was written by authors who are leaders in their field. Important and provocative questions dealing with recent developments are raised. Topics covered include:

To do or not to do? HLA typing in keratoplasty

Acute anterior uveitis and HLA-B27: what is new?

Keratouveitis: new aspects on diagnosis and management

Steroid sensitivity in uveitis

Is Behcet's retinal vasculitis different from idiopathic retinal vasculitis?

Is the diagnosis important in sight-threatening non-infectious uveitis?

Uveitis and multiple sclerosis: is there a real link?

Inflammation and AMD: what is the evidence?

Diabetic retinopathy: an inflammatory disorder?

Pathophysiology and its consequences.

This highly practical and clinically relevant volume is valuable to all those involved in the handling and treatment of patients with ocular inflammation. In addition, it provides fresh perspectives and insights into our current understanding of common disorders such as diabetic retinopathy and macular degeneration.

Zusammenfassung
The Essentials in Ophthalmology series represents an aged by readership acceptance of the first two series, unique updating publication on the progress in all sub- each of eight volumes. This is a success that was made specialties of ophthalmology. possible predominantly by the numerous opinion-lead- In a quarterly rhythm, eight issues are published cov- ing authors and the outstanding section editors, as well ering clinically relevant achievements in the whole field as with the constructive support of the publisher. There of ophthalmology. This timely transfer of advancements are many good reasons to continue andstill improve the for the best possible care of our eye patients has proven to dissemination of this didactic and clinically relevant be effective. The initial working hypothesis of providing information. new knowledge immediately following publication in the peer-reviewed journal and not waiting for the textbook G. K. Krieglstein appears to be highly workable. R. N. Weinreb We are now entering the third cycle of the Ess- tials in Ophthalmology series, having been encour- Series Editors Preface Our knowledge and understanding of immune-mediated the most recent research material available. The scope of diseases has increased exponentially over the past few the chapters ranges from well-recognized immune dis- years, especially in the areas of immunopathogenesis and ders such as cornea transplantation, uveitis and diabetic immunotherapeutics.

Inhalt
Histocompatibility Matching in Penetrating Keratoplasty.- Acute A nterior Uveitis and HLA-B27: 2 What's New?.- What Can the Aqueous Humour Tell Us About Uveitis?.- Is Diabetic Retinopathy an Inflammatory Disease? Inflammation as a Stimulus for Vascular Leakage and Proliferati on.- Steroid Sensitivity in Uveitis.- Multiple Sclerosis and Uveitis.- Inflammation in Age-Related Macular Degeneration: What is the Evidence?.- Age-Related Macular Degeneration: Immunological Factors in the Pathogenesis and Therapeutic Consequences.- Patterns of Retinal Vascular Involvement in the Diagnosis of Retinal Vasculitis.- Masquerade Syndromes.