This volume will be the first to provide a comprehensive description of tumor dormancy. It will define the clinical and biological aspects of this phenomenon, as well as the cellular and molecular mechanisms associated with tumor dormancy. Chapters will be authored by world-renewed experts who are conducting cutting-edge research in the field. A unique feature will be a conclusive paragraph detailing future development and foreseeable clinical applications at the end of each chapter. The volume will serve as a fundamental instrument for every researcher and clinician interested in the field of tumor dormancy as well as a means of disseminating stimulating concepts and prompting the development of innovative technological solutions.

Autorentext
Yuzhuo Wang, PhD, is Distinguished Scientist, Department of Experimental Therapeutics, BC Cancer Agency, Cancer Research Centre, Vancouver Prostate Centre, University of British Columbia, Department of Urologic Sciences, University of British Columbia, Vancouver, Canada.
Francesco Crea, PhD, is Post Doctoral Fellow, Department of Experimental Therapeutics, BC Cancer Agency, Cancer Research Centre, Vancouver Prostate Centre, University of British Columbia, Department of Urologic Sciences, University of British Columbia, Vancouver, Canada.

Zusammenfassung

Provides for the first time a comprehensive description of tumor dormancy while defining the clinical and biological aspects of this phenomenon, as well as the cellular and molecular mechanisms associated with tumor dormancy

Details future development and foreseeable clinical applications at the end of each chapter

Serves as a fundamental instrument for every researcher and clinician interested in the field of tumor dormancy as well as a means of disseminating stimulating concepts and prompting the development of innovative technological solutions

Inhalt
Chapter 1. Epigenetic regulation of cancer dormancy as a plasticity mechanism for metastasis initiation.- Chapter 2. Biological and clinical evidence for metabolic dormancy in solid tumors post therapy.- Chapter 3. Tumor dormancy, angiogenesis and metronomic chemotherapy.- Chapter 4. Immunoncology of Dormant Tumors.- Chapter 5. Thermodynamics and Cancer Dormancy: A Perspective.