Inhalt

The Statistical Analysis of Pharmacokinetic Data.- Mathematical Methods in The Formulation of Pharmacokinetic Models.- New Approaches to Uptake by Heterogeneous Perfused Organs: From Linear to Saturation Kinetics.- Basic Principles Underlying Radioisotopic Methods for Assay of Biochemical Processes in Vivo.- Tracer Studies of Peripheral Circulation.- Tracer Kinetic Modeling in Positron Computed Tomography.- Pharmacokinetic Models and Positron Emission Tomography: Studies of Physiologic and Pathophysiologic Conditions.- Kinetic Analysis of the Uptake of Glucose and Some of Its Analogs in the Brain Using the Single Capillary Model: Comments on Some Points of Controversy.- The Use of 11C-Methyl-D-Glucose for Assessment of Glucose Transport in the Human Brain: Theory and Application.- The Indicator Dilution Method: Assumptions and Applications to Brain Uptake.- Measurement of Ligand-Receptor Binding: Theory and Practice.- Acknowledgements.