Industry 4.0 technologies identified as the main contributor to the digitalization era. New technology delivers optimal outputs by utilization of effective resource. Therefore, smart technologies that has inventive and creative objects became critical to enterprise; recent studies shows that its led enterprises business such as SMEs to considerable investments, which many organizations over the world attempt to use innovative technologies such as IoT and AI, these technologies have potential on sustainable business models. In addition to that, innovation usage in business models led to significant benefits towards sustainability concept in SMEs marketplace. Furthermore, Sustainability objectives refers to corporate sustainability term, which integrate enterprise operations with social, educational, environmental and economic benefits, as process of decision-making can impact during sustainability implications. This book focus on the implementation of smart technologies for growing business, the book includes research articles and expository papers on the applications of technology on Decision Making, Healthcare, Smart Universities, Advertising, E-marketing, Public Sector and Digital Government, FinTech, RegTech. Some researchers also discussed the role of smart technologies in the current COVID-19 pandemic, whether in the health sector, education, and others. On all of these, the researchers discussed the impact of smart technologies on decision-making in those vital sectors of the economy.