This book is crafted for both novice simulation educators embarking on their teaching careers and seasoned subject matter experts seeking to enhance the effectiveness of their simulation programs. The book draws on the effort of a novice simulation educator under the guidance of two simulation experts with over 40 years of collective experience. Readers will embark on a transformative journey with this book, which is designed to empower readers who utilize simulation as a teaching tool. This book serves as a roadmap, leading educators toward a more organized and practical approach to conducting simulations. Covering a wide spectrum of topics, the book begins with insights into associated learning theories for simulation, providing valuable strategies for increasing learner engagement. Delving deeper, it explores various simulation modalities and locations, guiding educators to choose the best options for their teaching objectives. Within the pages of this handbook, readers will find detailed discussions on scenario design, simulation phases and crucial aspect of simulation best practices including prebriefing, implementation, facilitation and debriefing among others. In addition, the book addresses learner assessment and course evaluation, ensuring a well-rounded understanding of the entire simulation process. The authors invite readers to explore the wealth of knowledge within these pages, with the hope that they will gain valuable insights to elevate their simulation knowledge and skills and contribute to the continuous improvement of their teaching practices to the benefits of their students.