According to the World Health Organization, antimicrobial resistance is a major threat to global health because the number of alternative antibiotics is very limited. Antimicrobial resistance is a slow evolutionary process that has been accelerated by human activities in health, environment and agriculture sectors. Due to their wide application, antibiotics and their residues have been found in almost all food products and natural ecosystems. This book reviews the drivers, impact and mitigation of antimicrobial resistance, with focus on methods and targets.

Autorentext
Dr. Harsh Panwar is currently Assistant Professor in Dairy Microbiology at the Department of Dairy Microbiology of Guru Angad Dev Veterinary and Animal Sciences University, India. His research interests include antimicrobial resistance and its mitigation in dairy and food. Dr. Panwar has published more than 36 articles in high impact journals. He is editorial board member for several international journals. He has been awarded Young Scientist Award 2019 by the Association of Microbiologists of India; Indo-Australian Career Boosting Gold Fellowship 2018-19 by Department of Biotechnology, Government of India; Best Teacher 2019 and Best Researcher 2018 Award by Guru Angad Dev Veterinary and Animal Sciences University; DST Inspire Fellowship by Department of Science and Technology, Government of India; Commonwealth Scholarships by Commonwealth Scholarship Commission, UK; and University Gold Medal by Kurukshetra University Kurukshetra.
Dr. Chetan Sharma is working as a Research Advisor, Alpine Biomedicals Pvt. Ltd. Haryana, India. He has completed his M.Sc. and Ph.D. in Microbiology from Department of Microbiology, Kurukshetra University, Kurukshetra. He has published several research papers of international repute and serves as a reviewer for different journals. He has also edited and published one book by Nova Science Publishers, USA and two books from Springer Nature. His present research interest covers isolation of bioactive compounds from natural sources (plants), medical microbiology, antimicrobial resistance and probiotics.

Dr. Eric Lichtfouse is biogeochemist at the University of Aix-Marseille, France, and Visiting Professor at Xi'an Jioatong University. He has invented carbon-13 dating, a method allowing to measure the relative age of organic molecules occurring in different temporal pools of complex media. He is teaching scientific writing and communication, and has published the book Scientific Writing for Impact Factors, which includes a new tool the Micro-Article - to identify the novelty of research results. He is founder and Chief Editor of scientific journals and series in environmental chemistry and agriculture. He has founded the European Association of Chemistry and the Environment. He got the Analytical Chemistry Prize by the French Chemical Society, the Grand Prize of the Universities of Nancy and Metz, and a Journal Citation Award by the Essential Indicators.

Inhalt

Preface

Chapter 1 Antimicrobial resistance paradigm and One-health approach

Kumar Siddharth Singh, Santosh Anand, Sunny Dholpuria, Jitendra Kumar Sharma, Yogesh Shouche

Chapter 2 Global surveillance programs on antimicrobial resistance

Sunil Kumar, Mayank Chaudhary, Mukesh Yadav, Vikas Kumar

Chapter 3 Antimicrobial resistance, food systems and climate change

Mashkoor Mohsin, Ahtesham Ahmad Shad, Jabir Ali, Sajjad-ur-Rahman

Chapter 4 In silico approaches for prioritizing drug targets in pathogens

Mariana Santana, Stephane Fraga de Oliveira Tosta, Arun Kumar Jaiswal, Letícia de Castro Oliveira, Siomar C. Soares, Anderson Miyoshi, Luiz Carlos Junior Alcantara, Vasco Azevedo, Sandeep Tiwari

Chapter 5 Molecular and systems biology approaches for analyzing drug-tolerant bacterial persister cells

Xiangke Duan, Yang Fu, Liang Yang

Chapter 6 Role of gene editing tool CRISPR-Cas in the management of antimicrobial resistance

A Parul Sarma, Chhavi Jain, Manu Solanki, Rajesh Ghangal, Soma Patnaik

Chapter 7 Control of bacterial biofilms for mitigating antimicrobial resistance

Brij Pal Singh, Sougata Ghosh, Ashwini Chauhan

Chapter 8 - Intrusion of bacterial quorum-sensing for antimicrobial resistance mitigation: A pharmaceutical perspective

Sandeep Kumar, Shruti Shandilya, Kumar Siddharth Singh

Chapter 9 - Drug discovery for targeting drug resistant bacteria

Aikaterini Valsamatzi-Panagiotou, Katya B. Popova, Robert Penchovsky