As the leading cause of adult disability, stroke poses substantial economic and psychological burdens to populations around the world. Against this dismal backdrop, several novel "neurorestorative" approaches are being investigated as adjunctive treatments to physiotherapy. Stroke Recovery with Cellular Therapies discusses the promising investigations around the world on cell-based therapies to enhance recovery from stroke. Throughout this groundbreaking text, chapters detail the potential benefits of various types of cells and approaches for ischemic and hemorrhagic stroke, and all studies rely upon traditional histological and functional outcomes. Among the topics detailed in this volume are transplanting immortalized neural stem cells, transplantation of bone marrow stromal cells, adipose-derived stem cells, endogenous neural stem cells in tissue remodeling, and an investigation into the ethics of stem cell research. This text provides an overview of the field, stimulates ideas for further research, and will help serve as a foundation for cell-based therapies to move forward as a viable approach for stroke recovery in the future.

Zusammenfassung

Stroke is the leading cause of serious, long term disability. This book proposes different cellular therapies under investigation to promote neural regeneration after stroke. Authored by an international panel of scientists and clinicians, this volume is a vital, one-of-a-kind resource for all scientists interested in regenerative medicine.

Inhalt
Safety and Efficacy of Transplanting Immortalized Neural Stem Cells in Stroke Patients.- Transplantation of Bone Marrow Stromal Cells for the Treatment of Stroke.- Cord Blood Cells as a Treatment for Stroke.- Adipose-Derived Stem Cells as a Potential Therapy for Stroke.- Novel Imaging Modalities to Monitor Implanted Embryonic Stem Cells in Stroke.- Cell Transplantation for Intracerebral Hemorrhage.- Therapeutic Strategies Employing Endogenous Neural Stem Cells in Tissue Remodeling Following Ischemic Injury.- Ethics and Stem Cell Research.- Special Conditions in the Design of Clinical Stroke Trials for Cell Transplantation.