Stereotactic body radiation therapy (SBRT) has emerged as an innovative treatment for various primary and metastatic cancers, and the past five years have witnessed a quantum leap in its use. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.

Zusammenfassung

Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.

Inhalt

Introduction.- Safety and Quality Assurance.- CyberKnife system.- Novalis system.- HiART TomoTherapy system.- Treatment planning.- AAPM recommendation.- Launching a stereotactic body radiation therapy program.- Radiobiology of stereotactic body radiation therapy.- Primary Lung Cancer.- Primary Liver Cancer.- Prostate Cancer.- Cell Carcinoma.- Gynecologic Cancer.- Pancreatic Cancer.- Benign and Malignant Primary Spinal Tumors.- Non-Skull Base Head and Neck Cancer.- Skull Base Head and Neck Cancer.- Lung Metastasis.- Liver Metastasis.- Adrenal Metastasis.- Histologic Specific Metastasis.- Bone Metastasis.- Spinal Metastasis.- Reported toxicities associated with stereotactic body radiation therapy.- Normal tissue constraints.-Conduction of Trials in Stereotactic Body Radiation Therapy.