This book is a collection of reviews on the renal transport of organic substances. The first chapters deal with general aspects of the topic. The following articles treat the present knowledge on the renal trans­ port of specific compounds or classes of organic substances, whereas the fmal chapter on comparative physiology deals with the renal trans­ port of organic substances in non-mammalian vertebrates. The articles of this volume were presented in an abbreviated form as introductory lectures at a recent Symposium on Renal Transport of Organic Substances. This conference was organized by Prof. Deetjen and the editors, and was held in Innsbruck, Austria, in July 1980 at the Department of Physiology of the University of Innsbruck. During this conference the authors of the free communications (published as abstracts ill Renal Physiology, 2 (3), pp 135-166 (1980) as well as Drs. C. Gottschalk, T. Hoshi, K.C. Huang, J.P. Kokko, Ch. de Rouffignac, K. Scharer, BM. Schmidt-Nielsen, and J.A. Young, who acted as chair­ persons at the meeting, were invaluable contributors to the discussions of the topics reviewed in this volume. We hope that the book will be of value to nephrologists, to renal physiologists, and to those who are involved in teaching physiology, pharmacology, and internal medicine.

Inhalt

Methods for Studying Tubular Transport of Organic Substances.- Driving Forces for the Transport of Organic Solutes.- Electrical Aspects of Tubular Transport of Organic Substances.- Asymmetry of Membrane Functions in Transporting Cells.- Morphologic Analysis of Tubular Transport.- Renal Turnover of Substrates.- Recent Developments in Renal Handling of Glutamine and Ammonia.- Renal Transport of Amino Acids and Oligopeptides.- Renal Transport of Proteins.- Renal Transport of Urea.- Transport of D-Glucose in the Mammalian Kidney.- Renal Tubular Transport of Organic Cations.- Characteristics of p-Aminohippurate Transport in the Mammalian Kidney.- Renal Transport of Lactate.- Renal Transport of Oxalate.- Renal Handling of Urate.- Renal Transport of Drugs.- Renal Handling of Hormones.- Comparative Physiology of the Renal Transport of Organic Solutes.