Each chapter in this authoritative volume is written by a well-known physiologist who has contributed to our current understanding of renal function. Together the authors offer a unique, inside perspective on the historical record of the discipline, from its roots in the ancient world to the most recent findings of modern times. Among the many topics discussed are renal blood flow and the dynamics of glomerular filtration; the clearance concept in renal physiology; micropuncture and microperfusion; transport of electrolytes across renal tubules; and diuretics and renal drug development.

Inhalt

I Evolution of Renal Physiology From Earliest Times to William Bowman.- II Renal Blood Flow and Dynamics of Glomerular Filtration: Evolution of a Concept from Carl Ludwig to the Present Day.- III Clearance Concept in Renal Physiology.- IV Micropuncture and Microperfusion.- V From Renal Tissue Slices to Membrane Vesicles.- VI Transport of Electrolytes Across Renal Tubules.- VII Control of Sodium Excretion.- VIII Formation of Concentrated Urine.- IX Control of Vasopressin Release.- X Urea Excretion.- XI Acidification of Urine.- XII Tubular Transport of Organic Anions and Cations.- XIII Diuretics and Renal Drug Development.- XIV Comparative Renal Physiology.- Contributors.