Radiotherapy of Intraocular and Orbital Tumors presents a new approach to the role of radiation therapy in the management of ophthalmic cancer. The indications for ultrasonography, computed tomography, and magnetic resonance imaging studies are analyzed, and treatment techniques, together with their results, are described for each tumor. Particle beam and plaque irradiation are reviewed, and conservative and surgical management of radiation effects are detailed. In the past, most books on this subject included a chapter on radiotherapy but emphasized the dangers of radiation complications. However, great progress in understanding the effects of irradiation upon the tissues of the eye and orbit, new therapeutic equipment, and new imaging techniques (CT, MRI) allow for careful treatment planning. This book has taken the long overdue step of reconsidering the role of irradiation of the eye so that it may take its place as a respected, rather than feared, treatment in the combined modality approach so important today. Together with experts in relevant fields, the editors have produced a refreshingly clear and thoroughly referenced volume which will be a valuable asset to all ophthalmologists, radiation oncologists, pediatricians, endocrinologists, oncologists, and residents in training, as well as to students in these disciplines.

Inhalt

Section I Choroidal Tumors.- 1 Diagnostic Approaches to Posterior Uveal Melanoma.- 2 Histopathology of Uveal Malignant Melanoma and Other Uveal Tumors.- 3 Controversies in the Management of Posterior Uveal Melanoma.- 4 Treatment of Choroidal Melanomas with 106Ru/106Rh Beta Ray Applications.- 5 Primary Malignant Melanoma of the Uvea: Radioactive Plaque Therapy and Other Treatment Modalities.- 6 Particle Treatment of the Eye.- 7 Proton Beam Irradiation of Choroidal Melanomas at the PSI: Technique and Results.- 8 Histopathology Studies in Choroidal Melanomas After Unsuccessful Brachytherapy with 106Ru/106Rh Plaques.- 9 Thermoradiotherapy for Malignant Choroidal Melanoma: The Development of a New Microwave Hyperthermia System.- 10 Clinical Features and Management of Choroidal Hemangiomas, Including Those Occurring in Association with Sturge-Weber Syndrome.- 11 Radiation Therapy of Choroidal Metastases.- Section II Retinal Tumors.- 12 Diagnosis and Management of Retinoblastoma.- 13 Genetics of Retinoblastoma.- 14 Histopathology of Retinoblastoma.- 15 Coagulation Treatment and Surgery in Retinoblastoma.- 16 Plaque Brachytherapy in the Treatment of Retinoblastoma.- 17 Hyperthermia in the Treatment of Intraocular Tumors, in Particular Retinoblastoma.- Section III Orbital Tumors.- 18 Orbital Rhabdomyosarcoma.- 19 Optic Pathway Glioma.- 20 Radiation Therapy for Orbital Metastases.- 21 Graves' Disease.- 22 Management of Orbital Lymphoma.- 23 Lymphoid Tumors of the Orbit.- 24 Tumors of the Eyelids and Their Treatment by Radiotherapy.- 25 Conjunctival Tumors and Their Radiotherapy.- 26 Epithelial Tumors of the Lacrimal Gland and Lacrimal Sac.- Section IV Clinical Evaluation and Surgical Techniques.- 27 Neurologic Symptoms and Signs in Ocular and Orbital Tumors.- 28 Radiation-Related Orbital Injury: Clinical Manifestations and Considerations for Surgical Repair.- 29 Effects of Ionizing Radiation on the Conjunctiva, Cornea, and Lens.- Section V Diagnostic Procedures.- 30 Imaging of Diseases of the Orbit.- 31 Ultrasonic Diagnosis in Ophthalmologic Oncology.- 32 Imaging Studies of Intraocular Tumors.- 33 Fluorescein Angiography of Ocular Tumors.- Section VI Radiotherapeutic Techniques.- 34 Radiation Techniques for the Treatment of Retinoblastoma and Orbital Tumors.- 35 Physical Aspects of Eye Plaque Brachytherapy Using Photon Emitters.- 36 Dosimetry of Ru/Rh-106 Ophthalmic Applicators.- 37 Ocular Iodine Plaque Therapy: Dosimetry and Treatment Planning.- 38 Radiosensitivity of Ocular and Orbital Structures.- 39 Morphologic Changes After Iodine-125 Plaque Irradiation of Rabbit Eyes.- 40 Morphologic Changes After Fractionated External Beam Therapy of Minipig Eyes.- List of Contributors.