Proceedings of a Conference at the Strahlenzentrum der Justus-Liebig-Universität, Gießen, Germany, October 6-10, 1975. Organized in cooperation with Dt. Ges. f. Biophysik. Cospons. by the Comm. of the Europ. Communities, DirectorateGeneral Research, Science and Education, Biology Div.

Inhalt

• On the Rationale of this Conference.- I Radiation and Metabolic Key Processes.- 1. Radiation Action on Biochemical Key Processes: An Introduction.- 2. On the Transcriptional Organization of the Ribosomal RNA Genes of Yeast.- 3. Control of DNA Polymerase Activity in Synchronized Growing Yeast after X-Irradiation.- 4. DNA-Specific Labelling by Deoxyribonucleoside 5?-Monophosphates in Saccharomyces cerevisiae.- 5. Studies on DNA Synthesis in Saccharomyces cerevisiae.- 6. Metabolism of Yeast Cells after UV- and X-Ray Irradiation.- 7. Synthesis of the Inducible Enzyme Arginase in Irradiated Yeast Cells.- 8. Synthesis of RNA after Irradiation in Resistant and Sensitive Strains of the Slime-Mould Dictyostelium discoideum.- II Repair and Recovery.- 1. Repair in Yeast.- 2. Properties and Function of Escherichia coli DNA Polymerase I.- 3. Action of Sublethal Concentrations of SO2 on Repair by Budding Yeast after Ionizing and UV Radiation.- 4. Reparable and Irreparable Damage in Yeast Cells after Low LET-Irradiation.- 5. Survival of Yeast after Heavy Ion Irradiation.- 6. Incorporation of (Methyl 3H) 5?-dTMP into DNA of Diploid Yeast Cells as Tracer of Liquid Holding Recovery after X-Ray Irradiation.- 7. Influence of Intracellular Adenosine-Triphosphate Concentration on Survival of Yeast Cells Following X-Irradiation.- 8. Split Dose Recovery and Liquid Holding Recovery in Diploid Yeast Exposed to Fractionated X-Irradiation.- 9. Repair of Damage Induced by Near Ultraviolet Light Plus Furocoumarin in Saccharomyces cerevisiae.- 10. Postreplication Repair of DNA in Mammalian Cells: A Discussion of the Mechanisms and Biological Importance.- 11. Radiation-Induced Mutagenesis and Mechanisms of Repair in the Yeast, Schizosaccharomyces pombe.- 12. Accumulation of Replicative DNA Intermediates in Response to Damage of DNA in Tetrahymena pyriformis.- 13. Recovery from Radiation Damage Mediated by Somatic Cell Hybridisation.- 14. The Effect of Liquid Holding on Survival and Mitotic Recombination of Two UV-Sensitive Saccharomyces Diploids.- 15. Over-Repair in Closterium: Increased Radio-resistance Caused by an Earlier Exposure to Radiation.- 16. L5178Y Cell Strains Cross-Sensitive to X-Rays and UV-Light: Similarities and Differences in Recovery at the Cellular Level.- 17. Detection of Hybrid DNA Formed during Mitomycin C-Induced Sister Chromatid Exchange in Chinese Hamster Cells.- 18. Dependence of Photoreactivating Enzyme -Substrate Complex Formation in Saccharomyces on Liquid Holding Treatment.- 19. Evaluation of the Action Spectrum of Yeast Photoreactivation in vivo by Means of Pulsed Dye Lasers.- III Cell Division and Progression.- 1. Effects of UV- and Ionizing Radiation on Mitosis and Enzyme Regulation in the Synchronous Nuclear Division Cycle of Physarum polycephalum.- 2. The Molecular Basis for the Control of Cell Division.- 3. Cell Division and the Effects of Cell Age upon Radiation Sensitivity in Yeast.- 4. Budding and Division Delay in Diploid Yeast after Irradiation.- 5. Synthesis of Histones in the Cell Cycle of Saccharomyces cerevisiae.- 6. Macromolecular Events Following Nutritional Shift-Up of Tetrahymena.- 7. Radiation-Induced Processes in Moss Cells: Short-Term and Long-Term Radiation Responses of Special Interest after Microbeam UV Irradiation of the Haploid Moss Cells of Funaria hygvometvica.- 8. Radiation Action on Lens Epithelial Cells.- 9. Radiation and Endocellular Control of Cell Proliferation.- Closing Lecture - Modern Trends and Creeds in Radiobiology.