Acute Ischemic Stroke: Imaging and Intervention is a comprehensive presentation of the state-of-the-art in the diagnosis and treatment of acute ischemic stroke. This book, the first of its kind, offers a practical review of recent advances in stroke neuroimaging, and the latest therapeutic options for this disease.

Written by an internationally recognized experts who are members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School, the book covers the pathophysiology, mechanisms and molecular manifestations of ischemic brain injury and its clinical presentations; the physical principles, and practical applications of CT, CT angiography and CT perfusion; a detailed discussion of MRI, MRA, as well as diffusion and perfusion MR imaging; and the clinical management of the acute ischemic stroke patient including intravenous thrombolysis and intra-arterial vascular recanalization.

Practical guidance is provided for the use of imaging in guiding therapeutic decisions efficiently. The book is richly illustrated with images and plentiful tables are available for easy reference. It will serve as a unique source of information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke

Zusammenfassung

Written by physicians from the Massachusetts General Hospital and faculty from the Harvard Medical School, the book distills years of experience in the day-to-day management of acute stroke patients, as well as leading-edge basic and clinical research, into a practical guide. With the growing awareness that modern CT and MR imaging can meaningfully improve the outcome of the acute stroke patient, this book provides the practical information to advance the capacities of providers in delivering the most advanced care for this disease.

Inhalt
Fundamentals of Acute Ischemic Stroke.- Ischemic Stroke: Basic Pathophysiology and Neuroprotective Strategies.- Causes of Ischemic Stroke.- Imaging of Acute Ischemic Stroke.- Unenhanced Computed Tomography.- Stroke CT Angiography (CTA).- CT Perfusion (CTP).- Conventional MRI and MR Angiography of Stroke.- Diffusion MR of Acute Stroke.- Perfusion MRI of Acute Stroke.- Acute Stroke Imaging with SPECT, PET, Xenon-CT, and MR Spectroscopy.- Intervention in Acute Ischemic Stroke.- Clinical Management of Acute Stroke.- Intravenous Thrombolysis.- Endovascular Treatment of Acute Stroke.- Epilogue: CT versus MR in Acute Ischemic Stroke.