Lung ventilation is driven by a complex neural regulatory network, and apart from conditions typically observed during a disease state, it is sensitive to functional dysregulation. This book focuses on a wide variety of pulmonary topics including inflammation, infection, cancerogenesis, hypoxia, and stress. The chapters deal with the pathophysiologic background of processes and mechanisms whereby abnormal or undesired conditions develop and progress. The exemplary topics concern the genotyping of mutations involved in the development of lung cancer, which helps target molecular anticancer therapy, or the advances in computed tomography technology employed in pulmonary diagnostics. Functional cardio-respiratory changes associated with a particular disease or resulting from disease, or dysautonomic state due to affective disorder or hypokinesia of spaceflight microgravity also are tackled. The book is intended for medical researchers and clinicians, notably pulmonologists, internists, family doctors, and all interested in this exciting area of science.

Inhalt

Chapter 1. Adiponectin and Mortality in Smokers and Non-Smokers of the Ludwigshafen Risk and Cardiovascular Health (LURIC) Study, G.E. Delgado, R. Siekmeier, W. März, M.E. Kleber.- Chapter 2. Heart Rate Variability and Arrhythmic Burden in Pulmonary Hypertension, C. Witte, J.U. Meyer zur Heide genannt Meyer-Arend, R. Andrié, J.W. Schrickel, C. Hammerstingl, J.O. Schwab, G. Nickenig, D. Skowasch, C. Pizarro.- Chapter 3. Cardiac Vagal Control and Depressive Symptoms in Response to Negative Emotional Stress, I. Tonhajzerova, Z. Visnovcova, A. Mestanikova, A. Jurko, M. Mestanik.- Chapter 4. Effect of Simulated Microgravity and Lunar Gravity on Human Inspiratory Muscle Function: 'Selena-T' 2015 Study, M.O. Segizbaeva, N.P. Aleksandrova, Z.A. Donina, E.V. Baranova, V.P. Katuntsev, G.G. Tarasenkov, V.M. Baranov.- Chapter 5. Airway Evaluation with Multidetector Computed Tomography Post-Processing Methods in Asthmatic Patients, M. Patyk, A. Obojski , . Gojny, B. Panaszek, U. Zaleska-Dorobisz.- Chapter 6. Genotyping of EGFR Mutations from Bronchial Cytological Specimens in Slovakian Lung Cancer Patients, K. Baluchova, M. Zahradnikova, P. Bakes, S. Trubacova, H. Novosadova, E. Halasova, I. Majer, P. Hlavcak.- Chapter 7. Antiinflammatory Effect of N-Acetylcysteine Combined with Exogenous Surfactant in Meconium-Induced Lung Injury, P. Mikolka, J. Kopincova, L. Tomcikova Mikusiakova, P. Kosutova, A. Calkovska, D. Mokra,- Chapter 8. Pertussis: History of the Disease and Current Prevention Failure, E. Kuchar, M. Karlikowska-Skwarnik, S. Han, A. Nitsch-Osuch.- Chapter 9. Awareness of Influenza and Attitude Toward Influenza Vaccination among Medical Students, A. Banaszkiewicz, E. Talarek, J. liwka, F. Kazubski, I. Maecka, J. Stryczyska-Kazubska, W. Dziubak, E. Kuchar.- Chapter 10. Pathogens Causing Upper Respiratory Tract Infections in Outpatients, A. Jama-Kmiecik, M. Frej-Mdrzak, J. Sarowska, I. Choroszy-Król.