Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations and advances in prostate cancer and may be used as a rapid reference text for readers.

The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth.

Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, provides readers with a general reference for prostate cancer from prevention to therapy and will be of value to clinicians, scientists, and administrators who strive to solve the cancer problem.

Inhalt
Biology and Imaging.- Xenograft Models of Human Prostate Cancer.- The Pathology of Human Prostatic Atrophy and Inflammation.- Tissue Microarrays in Prostate Cancer Research.- Prostate (Cancer) Stem Cells.- Cancer-Host Interactions.- Androgen Receptor Function in Prostate Cancer Progression.- Hedgehog Signaling in Development and Cancer.- Cholesterol, Cell Signaling, and Prostate Cancer.- Gene Therapy for Advanced Prostate Cancer.- Role of Transforming Growth Factor-? in Immunotherapy of Prostate Cancer.- Biology and Therapeutic Basis of Prostate Cancer Bone Metastasis.- Molecular Imaging.- Quantum Dot Nanotechnology for Prostate Cancer Research.- Genetics.- Expression Profiling of Prostate Cancer Progression.- Somatic Alterations in Prostate Cancer Progression.- Linkage Studies of Prostate Cancer Families to Identify Susceptibility Genes.- Somatic DNA Methylation Changes and Prostatic Carcinogenesis.- Telomeres, Telomerase, Chromosome Stability, and Prostate Cancer.- Therapeutics.- Racial Differences in Prostate Cancer Mortality.- Radiotherapy for the Treatment of Locally Advanced Prostate Cancer.- Recombinant Antibody Candidates for Treatment of Prostate Cancer.- Differentiation Agents and Epigenomic Therapies.- Taxane-Based Chemotherapy for Prostate Cancer.- Co-Targeting Therapeutics for Hormone Refractory Prostate Cancer.- Intercellular Targets of Prostate Cancer.- Novel and Efficient Translational Clinical Trial Designs in Advanced Prostate Cancer.