This book constitutes the proceedings of the 16th Asian Symposium on Programming Languages and Systems, APLAS 2018, held in Wellington, New Zealand, in December 2018.The 22 papers presented in this volume were carefully reviewed and selected from 51 submissions. They are organized in topical sections named: types; program analysis; tools; functional programs and probabilistic programs; verification; logic; and continuation and model checking.

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Types.- Program Analysis.- Tools.- Functional Programs and Probabilistic Programs.- Verification.- Logic.- Continuation and Model Checking.