Prefaces of textbooks are generally meant to give editors an opportunity to express the rationale for the creation of yet another textbook. It is rare to find an author or editor who does not believe that his/her book fills a very specific need. This editor is no exception. With the incredible proliferation of medical textbooks in recent years, it has become difficult to find an empty niche for yet another text. Nevertheless, the editors and authors of Principles of Medical Therapy in Pregnancy have been impressed by one very clearly appreciated void: While the association of medical disorders with pregnancy is increasing in frequency as improved medical care allows more patients with medical diseases to conceive, an authoritative text covering the issue, comparable to an authoritative text in internal medicine, has been missing. With pregnancy representing a very specific disease situation-different from the nonpregnant state in diagnosis, management, and course of disease-a detailed textbook addressing all these issues for both the internist and the obstetrician seemed urgently needed.

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I. General Aspects of Medical Care during Pregnancy.- 1. Principles of Internal Medicine in Pregnancy.- 2. Fertility Control in the Female Patient with Medical Disease.- 3. Medical Records and Statistics during Pregnancy.- Appendix I-Prenatal Chart Model.- Appendix II-AntePartum Risk Factors.- 4. Physiologic Changes in Normal Pregnancy.- Appendix I-Laboratory Values in Pregnancy.- 5. Diagnostic Procedures.- 6. Obstetric Ultrasound in the Management of Pregnancy Complicated by Maternal and Fetal Disease.- 7. Principles of Drug Therapy in Pregnancy.- 8. Drug Abuse in Pregnancy.- Appendix I-Drugs, Category D, X: Effects on the Fetus and Mother.- 9. Alcohol.- 10. Prevention of Alcohol-Related Birth Defects.- 11. Tobacco Smoking.- 12. Environment and Pregnancy.- 13. Effects of Pregnancy on Work Performance.- 14. Maternal versus Fetal Rights.- II. Hormonal Diseases.- 15. Pregnancy Endocrinology.- 16. Endocrinology of the Placenta.- 17. Endorphins in Fetomaternal Physiology.- 18. Disorders of the Hypothalamus and Pituitary in Pregnancy.- 19. Thyroid Diseases in Pregnancy.- 20. Disorders of the Adrenal in Pregnancy.- 21. Diabetes in Pregnancy.- 22. Lactation during Pregnancy.- 23. The Pineal Gland.- 24. Ectopic Hormone Production in Pregnancy.- III. Metabolic Diseases.- 25. Metabolism during Pregnancy.- 26. Disorders of Amino Acid Metabolism.- 27. Maternal Hyperphenylalaninemia.- 28. Disorders of Nucleic Acid Metabolism in Pregnancy.- 29. Disorders of Metals and Metalloproteins.- 30. Disorders of Carbohydrate Metabolism.- 31. Disorders of Lipid Metabolism in Pregnancy.- 32. Disosrders of Connective Tissue.- IV. Nutritional Requirements and Disturbances.- 33. Vitamins and Minerals in Pregnancy.- 34. Normal Fetal Growth.- 35. Effects of Maternal Malnutrition and Obesity on Pregnancy Outcome.- Appendix I-Daily Dietary Allowances for Calories, Proteins, Vitamins, and Minerals.- V. Diseases Caused by Chemical and Physical Agents.- 36. Diseases Caused by Venoms, Bites, and Stings.- 37. Radiation Injury.- 38. Electrical Injuries.- 39. Drowning and Near Drowning.- 40. Chemical Intoxications.- 41. Common Poisons.- 42. Heavy Metals and Pregnancy.- VI. Infectious Diseases.- A. General Aspects of Infectious Diseases.- 43. An Approach to Infectious Diseases.- 44. Hospital-Acquired Infections.- 45. Bacteremia and Septic Shock.- 46. Localized Infections and Abscesses in Pregnancy.- 47. Chemotherapy of Infection.- 48. Acute Bacterial Diarrhea and Bacterial Food Poisoning.- 49. Prevention of Infection: Immunization and Antimicrobial Prophylaxis.- B. Infections Caused by Gram-Positive Cocci.- 50. Pneumococcal Infections.- 51. Staphylococcal Infections.- 52. Streptococcal Infections.- C. Infections Caused by Gram-Negative Cocci.- 53. Meningococcal Infections.- 54. Gonococcal Infections.- D. Aerobic Bacterial Infections.- 55. Gram-Negative Bacillary Infections during Pregnancy.- 56. Chancroid.- 57. Anthrax.- 58. Listeriosis.- 59. Diphtheria.- 60. Cholera.- 61. Campylobacter Infections.- 62. Bartonellosis.- 63. Granuloma Inguinale.- 64. Legionnaires' Disease.- E. Anaerobic Bacterial Infections in Pregnancy.- 65. Diseases Caused by Anaerobic Bacteria.- F. Infections Caused by Mycobacteria, Ectoparasites, and Spirocheta.- 66. Mycobacterial Diseases.- 67. Scabies, Lice, and other Ectoparasites.- 68. Syphilis.- 69. Nonvenereal Treponematoses.- 70. Leptospirosis.- 71. Relapsing Fever.- G. Infections Caused by Higher Bacteria, Fungi, Rickettsia, Mycoplasma, and Chlamydia.- 72. Infections Caused by Fungi and Higher Bacteria.- 73. Rickettsial Diseases in Pregnancy.- 74. Respiratory Infection with Mycoplasma pneumoniae.- 75. Chlamydial Infections.- H. Viral Infections.- 76. Introduction to Viral Infections in Pregnancy.- 77. General Considerations of Viral Respiratory Diseases.- 78. Common Viral Respiratory Illnesses.- 79. Influenza.- 80. Measles.- 81. Rubella.- 82. Smallpox.- 83. Chickenpox and Herpes Zoster.- 84. Other Viral Exanthematous Diseases.- 85. Herpes Simplex Viruses.- 86. Cytomegalovirus Infections.- 87. Epstein-Barr Virus Infections Including Infectious Mononucleosis.- I. Central Nervous System Viruses.- 88. Approach to the Patient with Aseptic Meningitis or Encephalitis.- 89. Enteric Viruses.- 90. Mumps.- 91. Rabies.- 92. Arboviruses.- 93. Arenaviruses.- 94. Diseases Caused by Slow Viruses.- J. Miscellaneous and Presumptive Viral Infections.- 95. Warts and Molluscum Contagiosum.- 96. Cat Scratch Disease.- K. Protozoan and Helminthic Infections.- 97. Protozoan Infections in Pregnancy.- 98. Helminthic Infections in Pregnancy.- L. Infections of the Urinary Tract and Vagina.- 99. Urinary Tract Infections in Pregnancy.- 100. Vaginitis during Pregnancy.- VII. Cardiovascular Diseases.- 101. The Evaluation of the Cardiac Patient during Pregnancy.- 102. Cardiovascular Physiology of the Normal Pregnancy.- 103. Cardiovascular Drugs in Pregnancy.- 104. Rheumatic Heart Disease.- 105. Congenital Heart Diseases and Pregnancy.- 106. Infective Endocarditis in Pregnancy.- 107. Gestation and Myocarditis.- 108. Diseases of the Pericardium in Pregnancy.- 109. Peripartal Cardiomyopathy.- 110. Hypertrophic Cardiomyopathy in Pregnancy.- 111. Coronary Artery Disease in Pregnancy.- 112. Aneurysms of the Aorta and its Major Branches.- 113. Anesthesia for Cardiac Surgery during Pregnancy.- 114. Arrhythmias in Pregnancy.- 115. Cardiac Surgery and Pregnancy.- 116. Thrombophlebitis and Pulmonary Embolism.- 117. Management of Thrombotic Disorders in Pregnancy.- VIII. Pulmonary Diseases.- 118. Pulmonary Physiology and Pulmonary Diseases in Pregnancy.- IX. Hypertension.- 119. HypertensiveDisorders in Pregnancy.- X. Renal and Urinary Tract Diseases.- 120. Renal Function and Volume Homeostasis during Pregnancy.- 121. Pregnancy in Women with Chronic Renal Disease.- 122. Acute Renal Failure in Pregnancy.- XI. Alimentary Tract.- 123. The Oral Cavity.- 124. The Esophagus and Stomach.- 125. Small and Large Bowel Disease in Pregnancy.- XII. Hepatobiliary Tract and Pancreas.- 126. Liver Disease: General Considerations.- 127. Liver Diseases of Pregnancy.- 128. Viral Hepatitis.- 129. Pregnancy and Chronic Liver Disease.- 130. Acute Pancreatitis.- XIII. Diseases of the Eye and Ear.- 131. Common Disturbances of Vision and Ocular Movement and Surgery of the Eye in the Pregnant Patient.- 132. Otolaryngology: Head and Neck Problems in Pregnancy.- XIV. Psychiatric, Neurologic, and Striated Muscle Diseases.- 133. Psychosocial Stress and Pregnancy.- 134. Sexuality and Pregnancy.- 135. Neurosis and Psychiatric Diseases.- 136. Psychotropic Drugs.- 137. Barbiturates.- 138. Opiates and Synthetic Analgesics.- 139. Neurologic Disorders in Pregnancy.- 140. Diseases of the Striated Muscles in Pregnancy.- XV. Immunologic Diseases.- 141. Immunologic Diseases: General Considerations.- 142. Immunologic Disorders.- 143. The HLA Co…