The book covers the epidemiology, pathology, molecular biology, clinical features, diagnosis, and treatment of Hodgkin and non-Hodgkin lymphomas in children and adolescents. It is a combined effort of investigators who are leaders in the field of childhood lymphomas. Introductory chapters on Hodgkin and non-Hodgkin lymphomas in children provide a concise historical overview. All chapters have a standalone structure and those regarding the individual subtypes of lymphomas provide up-to-date results of recent clinical trials and practical guidelines for work-up and treatment. The pathology chapters are comprehensive and include excellent photographs as well as detailed review of the scientific advances pertaining to the molecular pathogenesis of each type of malignant lymphoma seen in childhood. There is also a concise chapter on post-transplant lympho-proliferative disease and lymphomas associated with congenital and acquired immunodeficiency states. The book is at the level of sub-specialists in pediatric hematology and oncology, radiation oncology, pediatric surgery and hematopathology.

Zusammenfassung
T is is the f rst edition of Pediatric Lymphomas. T e ment of both Hodgkin and non-Hodgkin lymphomas, editors have been colleagues for more than 25 years and lymphoproliferative disorders associated with - and have been involved in the design and coordination munodef ciency. In addition, three chapters focus on of clinical trials and multimodality approaches for the pathology, molecular biology, and genetics of children with Hodgkin and non-Hodgkin lymphomas. Hodgkin and non-Hodgkin lymphoma including the Progress in elucidating the pathogenesis and in the di- rare cutaneous lymphomas. We hope that Pediatric agnosis and treatment of lymphomas in children has Lymphomas will be a useful resource for practitioners been one of the great success stories in pediatric oncol- from the many dif erent disciplines involved in the ogy. Prior to 1970, fewer than 20% of children with comprehensive care of children with lymphomas. malignant lymphomas survived. Today, more than T e authors are all leading experts in the area of 90% of children diagnosed with Hodgkin lymphoma childhood lymphomas. We wish to thank them for all survive and more than 80% of children with non- of the time and ef ort that went into their contribu- Hodgkin lymphoma are considered cured. Continued tions. If this f rst edition is helpful to our diverse re- improvement in survival has occurred as the result of ership, it is because of the authors.

Inhalt
and Historical Background: Pediatric Hodgkin Lymphoma.- Biology and Pathology of Hodgkin's Disease.- Treatment of Pediatric Hodgkin Lymphoma.- Treatment of Relapsed/Refractory Hodgkin Lymphoma.- Non-Hodgkin's Lymphoma.- Biology and Pathology of Pediatric Non-Hodgkin Lymphoma.- B-Cell Lymphoma/Burkitt Lymphoma.- Anaplastic Large-Cell Lymphoma.- Precursor B and Precursor T-Cell Lymphoblastic Lymphoma.- Cutaneous T-Cell Lymphomas and Rare T-Cell Non-Hodgkin Lymphomas.- Lymphoproliferative Disorders Related to Immunodeficiencies.- Late Effects Following Lymphoma Treatment.