After obesity and asthma, hypertension is the most frequently occurring chronic disease in childhood, as well as an important precursor of adult cardiovascular disease. In Pediatric Hypertension, a multidisciplinary panel of physicians, clinicians, and academicians comprehensively review all aspects of this disease to create the most state-of-the-art treatment of the subject currently available. The topics covered range from the regulation and assessment of blood pressure in children, to its evaluation and day-to-day management. The authors not only outline the pathophysiology of hypertension in children, but also offer current information on blood pressure measurement, the proper techniques for diagnosis, the assessment of hypertensive end-organ damage even in childhood, and the use of ambulatory blood pressure monitoring. Additional chapters address the genetic background of hypertension, the characterization of the disease from infancy through the teen years, and the appropriate treatment of hypertension-with and without drugs-including details of current studies of antihypertensive medications and their use. Definitions of hypertension in children, predictors of future hypertension, risk factors-race and ethnicity, diet, obesity, and society-and special populations are discussed at length. Comprehensive chapters on both primary and secondary hypertension in children point out differences in presentation between the pediatric and adult populations.
Authoritative and current, Pediatric Hypertension offers pediatricians, family practitioners, and pharmaceutical scientists a comprehensive survey of what is currently known about childhood hypertension, as well as detailed practical advice for its optimal management.

Klappentext

The importance of hypertension in children and adolescents is becoming incre- ingly recognized by physicians and scientists in the 21st century. However, in contrast to the attention that hypertension has received in the adult population for the past three decades since the first Joint National Committee (JNC) report, research and clinical knowledge that involves hypertension in children is still very much in its own childhood. Pediatric Hypertension, edited by Drs. Portman, Sorof, and Ingelfinger, is undoubtedly the most up-to-date and clinically relevant contribution to the field of hypertension in children available because it brings together the numerous pathophysiologic, diagnostic, and therapeutic advances in the evaluation of high blood pressure in infants, children, and adolescents. The editors have carefully organized their volume into sections that cover blood pressure regulation in infants and children, blood pressure measurement issues, pat- physiology and clinical assessment for essential and secondary forms of hypertension during childhood, and nonpharmacologic and pharmacologic approaches to the tre- ment of hypertension in children.

Inhalt

Part I. Regulation of Blood Pressure in Children Neurohumoral Regulation of Blood Pressure in Early Development Jeffrey L. Segar and Jean E. Robillard Cardiovascular and Autonomic Influences on Blood Pressure John E. Jones, Aruna R. Natarajan, and Pedro A. Jose Development of Circadian Time Structure and Blood Pressure Rhythms Erhard Haus and Michael H. Smolensky Part II. Assessment of Blood Pressure in Children: Measurement, Normative Data, Epidemiology Casual Blood Pressure Measurement Methodology Bruce Z. Morgenstern and Lavjay Butani Development of Blood Pressure Norms in Children Bonita Falkner Ambulatory Blood Pressure Methodology and Norms in Children Empar Lurbe and Josep Redon Epidemiology of Essential Hypertension in Children: The Bogalusa Heart Study Elaine M. Urbina, Sathanur R. Srinivasan, and Gerald S. Berenson Part III. Hypertension in Children: Definitions, Predictors, Risk Factors, and Special Populations Definitions of Hypertension in Children Jonathan M. Sorof Secondary Forms of Hypertension in Children Michael J. Dillon Essential Hypertension in Children Tej K. Mattoo and Alan B. Gruskin Sequelae of Hypertension in Children and Adolescents Stephen R. Daniels Monogenic and Polygenic Genetic Contributions to Hypertension Julie R. Ingelfinger Perinatal Programming and Blood Pressure Julie R. Ingelfinger Cardiovascular Reactivity in Youth: Toward a Gene-Environment Model of Stress-Induced Cardiovascular Disease Frank A. Treiber and Harold Snieder Familial Aggregation of Blood Pressure Harold Snieder Influence of Dietary Electrolytes on Childhood Blood Pressure Dawn K. Wilson Ethnic Differences in Childhood Blood Pressure Gregory A. Harshfield and Martha E. Wilson Childhood Obesity and Blood Pressure Regulation Albert P. Rocchini Social Environments, Agonistic Stress, and Elevated Blood Pressure in Urban Youth Craig K. Ewart Neonatal Hypertension Joseph T. Flynn Hypertension in Chronic Kidney Disease Franz Schaefer and Otto Mehls Hypertension in End-Stage Renal Disease Karl Schärer Part IV. Evaluation and Management of Pediatric Hypertension Diagnostic Evaluation of Pediatric Hypertension Rita D. Swinford and Ronald J. Portman Nonpharmacologic Treatment of Pediatric Hypertension Bruce S. Alpert, Michael Hasselle, and Sidney Ornduff Approach to the Pharmacologic Treatment of Pediatric Hypertension Douglas L. Blowey Pediatric Antihypertensive Trials Thomas G. Wells Management of Hypertensive Emergencies Raymond D. Adelman Index