The proceedings of the 1987 IUPHAR symposium held in Sydney, Australia are fully documented. Over 100 scientists from 16 countries attended the three-day conference, during which time 68 multi-disciplinary presentations concerning dopamine systems and their regulation were made.

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The status quo and the future, J.G.Cannon; structure-activity relationships for benzazepines as D-1-specific dopamine antagonists, A.Barnett et al; the development of potent and selective D-2 agonists of the 2-aminotetralin group - their clinical applications and their use in the isolation of the D-2 receptor, A.S.Horn et al; dopaminergic ergots, R.Markstein et al; autoreceptor agonists, H.Wikstrom; structural analyses predict the primary pharmacophore and secondary sites for the D-2 receptor, P.M.Beart and D.T.Manallack; structure-activity relationship of tetrahydroprotoberberines on central dopamine receptors, G.Z.Jin et al; D-1 and D-2 dopamine receptors - identification of photoaffinity labeling and purification by affinity chromatography, M.G.Caron et al; D-2 dopamine receptors - isolation and mechanism, P.G.Strange; intracellular ionic changes induced by dopamine receptor stimulation in mammotrophs - evidence for a K+ channel-linked dopamine D-2 receptor, M.Memo et al; dopamine D-2 receptor agonists decrease the basal level of inositol 1,4,5-trisphosphate in rat striatal slices, M.Da Prada et al; D-2 receptor activation increases potassium conductance in substantia nigra zona compacta neurones in vitro, M.G.Lacey et al; different states of the dopamine D-1 receptor - fact or fantasy?, P.H.Andersen et al; purification of receptor-binding antipsychotics - comparison with D-2 dopamine receptor, Y.Nishizawa et al; electrophysiological investigation of D-1/D-2 receptor interactions in the substantia nigra and basal ganglia, J.R.Walters et al; biochemical insights in the D-1/D-2 receptor interactions, J.C.Stoof; dopamine D-1 and D-2 receptor differentiation revealed by behavioural studies in rats, J.Arnt et al; new selective D-1 and D-2 dopamine receptor agonists as further probes for behavioural interactions between D-1 and D-2 systems, J.L.Waddington et al; neurobiology of supersensitive D-1 and D-2 dopamine receptors after 6-hydroxydopamine lesions, G.R.Breese et al; dopamine D-1 and D-2 receptor-mediated inhibition and excitation of caudate neurons induced by respective high and low concentrations of dopamine in vitro, A.Akaike et al; long-term apomorphine produces both supersensitive and subsensitive responses to D-1 and D-2 receptor agonists, E.M.Wallis; "priming" phenomena in the expression of D-1 and D-2 receptor supersensitivity, M.Morelli et al; regulation of striatal D-1 dopamine receptor density by D-1 and D-2 antagonists, S.J.Boyson et al; endogenous dopamine release from brain slices - comparisons with radiolabelled release and regulation by autoreceptors, H. Herdon and S.R.Nahorski; regulation of dopamine release by muscarinic receptors, M.Raiteri et al; repeated cocaine administration results in supersensitive nigrostriatal D-2 dopamine autoreceptors, N.R.Zahniser et al; functional presynpatic D-2 and postsynaptic D-1 dopamine receptors in the central nervous system, M.L.Dubocovich and J.G.Hensler. (Part contents)