Beschreibung
This book contains the refereed contributions from the 43rd annual meeting of ISOTT. The annual meetings of ISOTT bring together scientists from various fields (medicine, physiology, mathematics, biology, chemistry, physics, engineering, etc.) in a unique international forum. ISOTT conferences are a place where an atmosphere of interaction is created, where many questions are asked after each presentation and lively discussions occur at a high scientific level. This vivid interaction is the main motivation for members to participate and gain new ideas and knowledge in the broad field of oxygen transport to tissue. The proceedings include sessions covered various research topics including Multi-Modal Imaging/Spectroscopy & Instrumentation; Cancer Metabolism; Cellular Hypoxia and Mitochondrial Function; Brain Oxygenation and Function; Other Organ Function and Metabolism; Oxygen Transport in Sports, Diseases and Clinical Care; Acupuncture, Meridians, and Primo Vascular System; EPR, MRS and MRI.
Inhalt1. ISOTT from the Beginning: A Tribute to Our Deceased Members (Icons)
D. F. Bruley and E. E. Thiessen
Part ICell Metabolism, Tissue Oxygenation and Treatment
2. A Compelling Case for the Use of Perioperative Zymogen Protein C for Increased Patient Safety
D. F. Bruley, J. M. Abdallah, M. B. Streiff, T. W. McGuire, K. C. Bruley, M. Duncan, R. Duncan, E. E. Thiessen, M. White, K. C. Bruley, Jr., and S. B. Bruley
3. Clinical Evaluation of MP4CO: A Phase 1b Escalating-dose, Safety and Tolerability Study in Stable Adult Patients with Sickle Cell Disease
Peter E. Keipert
4. Protective Effect of Dl-3-n-butylphthalide on Recovery from Cardiac Arrest and Resuscitation in Rats
Le Zhang, Michelle A. Puchowicz, Joseph C. LaManna, and Kui Xu
5. Hypoxia-Induced Let-7d Has a Role in Pericyte Differentiation
Nilufer Esen, Anuush Vejalla, Rakhi Sharma, Jesse S. Treuttner, and Paula Dore-Duffy
6. Magnification of Cholesterol-Induced Membrane Resistance on the Tissue Level: Implications for Hypoxia
Ryan Shea, Casey Smith, and Sally C. Pias
7. Respiratory Pores on Ostrich Struthio camelus (Aves: Struthionidae) Eggshells
T. Koyama and A.J.D. Tennyson
8. Evaluation of both Free Radical Scavenging Capacity and Antioxidative Damage Effect of Polydatin
Ju Jin, Yan Li, Xiuli Zhang, Tongsheng Chen, Yifei Wang, and Zhiping Wang
9. Spectroscopic Studies on the Interaction of Pyridinoline Cross-linking in Type 1 Collagen with ZIF8-HB
Yashun Chen, Fangfang He, Wei Liu, and Jucheng Zhang
10. The Role of Free Radicals in the Photodynamic Treatment of Fibrotic Skin Diseases
Heping Yan, Yashun Chen, Jucheng Zhang, Wei Liu, and Rui Chen
Part IICancer Oxygenation and Metabolism
11. Tumor Hypoxia: Causative Mechanisms, Microregional Heterogeneities, and the Role of Tissue-based Hypoxia Markers
Peter Vaupel and Arnulf Mayer
12. Molecular Imaging of Tumor Hypoxia: Existing Problems and Their Potential Model-based Solutions
Kuangyu Shi, Sibylle I. Ziegler, and Peter Vaupel
13. Direct and Repeated Clinical Measurements of pO2 for Enhancing Cancer Therapy and Other Applications
Harold M. Swartz, Benjamin B. Williams, Huagang Hou, Nadeem Khan, Lesley A. Jarvis, Eunice Y. Chen, Philip E. Schaner, Arif Ali, Bernard Gallez, Periannan Kuppusamy, and Ann B. Flood
14. Impact of the Tumor Microenvironment on the Expression of Inflammatory Mediators in Cancer Cells
A. Riemann, A. Ihling, S. Reime, M. Gekle, and O. Thews
15. Comparing the Effectiveness of Methods to Measure Oxygen in Tissues for Prognosis and Treatment of Cancer
Ann Barry Flood, Victoria A. Satinsky, and Harold M. Swartz
16. Potential Indexing of the Invasiveness of Breast Cancer Cells by their Mitochondrial Redox Ratios
Nannan. Sun, He N. Xu, Qingming. Luo, and Lin Z. Li
17. Directional Migration of MDA-MB-231 Cells under Oxygen Concentration Gradients
D. Yahara, T. Yoshida, Y. Enokida, and E. Takahashi
18. Stress-induced Stroke and Stomach Cancer: Sex Differences in Oxygen Saturation
Maria Ulanova, Artem Gekalyuk, Ilana Agranovich, Victoria Rezunbaeva, Ekaterina Borisova, Aly Esmat Sharif, and Oxana Semyachkina-Glushkovskaya
Part IIIBrain Oxygenation and Function
19. Changes in Oxygenation Levels Precede Changes in Amplitude of the EEG in Premature Infants
Alexander Caicedo, Liesbeth Thewissen, Anne Smits, Gunnar Naulaers, Karel Allegaert, and Sabine Van Huffel
20. Effects of Pos...