This book contains most of the scientific contributions during the 48th annual conference of the International Society on Oxygen Transport to Tissue (ISOTT), which was held electronically in July 2021. It includes multidisciplinary contributions from scientists (physicists, biologists and chemists), engineers, clinicians and mathematicians and covers covers all aspects of oxygen transport from air to the cells, organs and organisms; instrumentation and methods to sense oxygen and clinical evidence.

Autorentext

Ursula Wolf, PhD is Professor and Director of the Institute of Complementary and Integrative Medicine at the University of Bern in Switzerland. Her research interests focus on integrative medicine, in particular patient centered research, integrative physiology, and clinical studies.

Felix Scholkmann, PhD is a lecturer at the University of Zurich and a Research Associate at the Biomedical Optics Research Laboratory (Dept. of Neonatology) of the University Hospital Zurich, University of Zurich in Switzerland, and at the University of Bern in Switzerland. His research mainly concerns the fields of neurophotonics and biomedical signal processing, as well as integrative neuroscience and physiology. He has authored or co-authored over 140 research papers, book chapters and reviews.

Joseph C. LaManna, PhD is The Jeannette M. and Joseph S. Silber Professor for the Study of Brain Sciences in the Department of Physiology & Biophysics at Case WesternReserve University. He has been a member of ISOTT since 1974 and served as Past President of the Society (2009). He is the Series Editor of the ISOTT Proceedings. He has been involved in cerebrovascular research for 40 years. His research is concerned with brain metabolism, energy and cerebral blood flow, angiogenesis and neurodegeneration. The role of these mechanisms in tissue response to pathological insults (stroke, cardiac arrest and resuscitation, hypoxia) is being actively investigated. His recent research has centered on ketones, cerebral angiogenesis and the role of hypoxia-inducible factor-1 in physiological adaptation to hypoxia, neuroprotection and ischemic preconditioning. He has authored or co-authored over 200 research papers and review chapters.