This book reviews the current application of molecular tools in cytopathology and serves as a concise handbook for those who provide care in this era of personalized medicine. Specifically, the text provides a comprehensive and concise review of the emerging molecular tests available clinically in different organ systems. It reviews the current data of molecular testing already applied in cytopathology, discusses some of the biomarkers with potential utility in cytopathology in the near future and reviews the technical challenges in applying and validating molecular tools in various cytologic materials. Molecular Cytopathology will serve as a valuable resource for cytopathologists, cytotechnologists, pathology trainees, and clinicians with an interest in molecular applications in cytopathology.

Autorentext
Bin Yang, M.D., Ph.D.
Associate Professor of PathologyDirector of Molecular CytopathologyPathology & Laboratory MedicineCleveland Clinic Lerner College of Medicine9500 Euclid AvenueCleveland, OH 44195USA
Jianyu Rao, M.D., Ph.D.
Professor of Pathology and Epidemiology
Director of Cytopathology
Pathology and Laboratory MedicineRonald Reagan UCLA Medical Center10833 Le Conte AvenueLos Angeles, CA 90095
USA

Zusammenfassung
This book reviews the current applications of molecular tools in cytopathology and provides a concise handbook for those who provide care in this era of personalized medicine. Specifically, the text provides a comprehensive and concise review of the emerging molecular tests available clinically in different subspecialities of diagnostic pathology. It reviews the current data of molecular testing already applied in cytopathology, discusses some of the biomarkers with potential utility in cytopathology in the near future and reviews the technical challenges in applying and validating molecular tools in liquid-based cytologic materials. Molecular Cytopathology will serve as a valuable resource for cytopathologists, cytotechnologists, pathology trainees, and clinicians with an interest in molecular applications in cytopathology.

Inhalt

1. Introduction.- 2. Advantage of molecular testing using cytologic materials.- 3. Validation of molecular techniques in liquid-based specimens.- 4. Establishment of molecular cytology laboratory.- 5. Researches on molecular cytopathology.- 6. Molecular Biomarkers in cervical cytology.- 7. Molecular Biomarkers in thyroid cytology.- 8. Molecular Biomarkers in head and neck cytology.- 9. Molecular Biomarkers in pulmonary cytology.- 10. Molecular Biomarkers in breast cytology.- 11. Molecular Biomarkers in urine cytology.- 12. Molecular Biomarkers in hepatobiliary and pancreatic cytology.- 13. Molecular Biomarkers in mesothelioma and body fluid cytology.- 14. Molecular Biomarkers in soft tissue cytology.- 15. Molecular Biomarkers in brain tumors.- 16. Molecular cytopathology in therapeutic surveillance.