Inhalt

Metabolic Interconversion.- Automodification of Poly (ADP-ribose) Synthetase and DNA Repair.- cAMP-dependent Protein Kinase. Active Site Structure, Restricted Degradation, and Use in Assessing the Regulation of the Hormonal Response.- Classification of Protein Phosphatases Involved in Cellular Regulation.- The Mechanism of Action of Brain Cyclic AMP-dependent Protein Kinase: Structure of Active Site, Mechanism of Dissociation of the Holoenzyme, and Possible Biological Role of Its Subunits.- Regulation of Skeletal Muscle Phosphatases by Mn2+ and Sulfhydryl-Disulfide Interchange.- Regulation of Liver Phosphorylase Kinase.- Insulin Mediators and Their Control of Covalent Phosphorylation.- Regulation of Phosphofructokinase by Phosphorylation - Dephosphorylation - State of the Art.- The Control of Liver Phosphofructokinase by Fructose 2,6-Bisphosphate.- The Relationship Between Latent Phosphorylase Phosphatases and the Precursors of the Heat-stable Inhibitor in a Liver High-speed Supernatant.- Multimodulation of Phosphofructokinases in Metabolic Regulation.- Structure, Function, and Regulation of Mammalian Pyruvate Dehydrogenase Complex.- Regulation of Adipose Tissue Pyruvate Dehydrogenase by Insulin: Possible Messenger Role of Peroxide(s).- Proteolytic Modification.- Mast Cell Proteases.- Chemical Steps in the Selective Inactivation and Degradation of Glutamine Phosphoribosylpyrophosphate Amidotransferase in Bacillus subtilis.- Inactivation and Turnover of Fructose-1,6-Bisphosphatase from Saccharomyces cerevisiae.- Catabolite Inactivation of Phosphoenolpyruvate Carboxykinase and Aminopeptidase I in Yeast.- Metabolic Interconversion of Yeast Fructose-1,6-Bisphosphatase.- Fructose-1,6-Bisphosphatase Converting Enzymes in Rabbit Liver Lysosomes: Purification and Effect of Fasting.- Release and Modulation of Membrane-bound ?-Glutamyltrans-peptidase by Limited Proteolysis.- Inactivation of Cytosol Enzymes by a Liver Membrane Fraction.- Intracellular Protein Topogenesis.- Precursor Processing in the Biosynthesis of Rat Liver Cytochrome c Oxidase.- Characterization and Possible Pathophysiological Significance of Human Erythrocyte Proteinases.- Physiological Function and Catalytic Mechanism of Angiotensin Converting Enzyme.- Novel Aspects of Regulation.- Regulation of Glutamine Synthetase Degradation.- Mono ADP-ribosylation and Poly ADP-ribosylation of Proteins.- ADP-ribosylation of Nonhistone Chromatin Proteins in Vivo and of Actin in Vitro and Effects of Normal and Abnormal Growth Conditions and Organ-specific Hormonal Influences.- ADP-ribosylation of Ribonucleases.- Supramolecular Organization of Regulatory Proteins into Calcisomes: A Model of the Concerted Regulation by Calcium Ions and Cyclic Adenosine 3?: 5?-Monophosphate in Eukaryotic Cells.- Inhibition of Catalytic Subunit by Fragments of cAMP-dependent Protein Kinase Regulatory Subunit I and II.- Control of Mg2+ and Ca2+ Binding to Troponin C and Calmodulin by Phosphorylation of the Respective Holocomplexes Troponin and Phosphorylase Kinase.- Bacterial Prohistidine Decarboxylase: Kinetics of Conversion to the Active Enzyme.- Sulfation of a Cell Surface Component Correlates with the Developmental Program During Embryogenesis of Volvox carteri.- Structure, Possible Function, and Biosynthesis of VPg, the Genome-linked Protein of Poliovirus.- The Acetylcholine Receptor: Control of Its Synthesis, Stability, and Cell Surface Distribution.- x03B2;-Catecholamine-Stimulated Adenylate Cyclase; an Associating-Dissociating System.