This book includes best papers selected from more than 500 papers submitted at 25th International Conference on Man-Machine-Environment System Engineering (MMESE) 2025. It covers the best research topics and the latest development trends in MMESE theory and application. MMESE is a scientific study of the design concepts and quantitative analysis of a complex giant system using physiology, psychology, system engineering, computer science, environment science, management theory, education, and other related disciplines methods. MMESE focuses mainly on the relationship and the optimum combination between man, machine, and environment. The three optimized goals of the MMESE study are safety, efficiency, and economy. Researchers and professionals who study a human-centered interdisciplinary subject crossing above disciplines will be mostly benefited from the proceedings.

In 1981, with direct support from one of the greatest modern Chinese scientists, Xuesen Qian, Man-Machine-Environment System Engineering (MMESE), the integrated and advanced science research topic was established in China by Professor Shengzhao Long. In the letter to Shengzhao Long on October 22, 1993, Xuesen Qian wrote: "You have created a very important modern science subject and technology in China!".

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Professor Shengzhao Long is the founder of the Man-Machine-Environment System Engineering (MMESE) and the chairman of the Man-Machine-Environment System Engineering (MMESE) Committee of China, the chairman of the Beijing Kecui Man-Machine Environment System Engineering Technology Research Institute, and the former director of Ergonomics Lab of Astronaut Centre of China. In October 1992, he is honored by the Chinese Government National Specific Allowance. Professor Shengzhao Long graduated from the Shanghai Science and Technology University in 1965, China. In 1981, supported by the famous modern scientist Qian Xuesen, he founded MMESE theory.

Professor Balbir S. Dhillon is a professor of Engineering Management in the Department of Mechanical Engineering at the University of Ottawa, Canada. He has served as a chairman/director of Mechanical Engineering Department/Engineering Management Program for over ten years at the same institution. He has published over 345 (i.e., 201 journal + 144 conference proceedings) articles on reliability, safety, engineering management, etc. He has been on the editorial boards of 9 international scientific journals. In addition, Dr. Dhillon has written 34 books on various aspects of reliability, design, safety, quality, and engineering management published by Wiley (1981), Van Nostrand (1982), Butterworth (1983), Marcel Dekker (1984), Pergamon (1986), etc. His books are being used in over 85 countries, and many of them are translated into languages such as German, Russian, and Chinese.

Professor Long Ye is an expert of the Transportation Safety Expert Group of the Ministry of Transport of China and the winner of the New Century Excellent Talents Supporting Plan of Ministry of Education of China and Baosteel Outstanding Teacher Award. As the director of "Research Center for Occupational Adaptability of Key Positions in Railway Transportation", Prof. YE has been leading the research team focusing on human resource management, safety management, and occupational health in the field of railway transportation. The research team is the only one in China that provides professional assessment of driving adaptability for the selection of high-speed railway drivers. In more than 30 years of researching, Prof. YE has undertaken variety of national-level and provincial-level projects, such as the National Key Research and Development Program of China.