This book discusses the potential of magnetic nanoparticles in cancer therapy. It reviews the synthesis of magnetic nanoparticles - which, due to their small size and processability, have become widely used in various biomedical applications - and their role in cancer diagnosis, drug delivery, and personalized medicine. It presents the applications of magnetic nanoparticle in the destruction of tumor cells by heating them to their apoptosis threshold.

It also introduces the new perspective in the development of magnetic field induced drug release in the cancer treatment. Importantly, the book covers the innovative three arm approach in cancer treatment by magnetic nanoparticles through inducing apoptosis, activating the immune response, and targeted-drug delivery.

It highlights various novel approaches to improve the biocompatibility, half-life, and biodegradability of magnetic nanoparticles.

In closing, the book offers comprehensive descriptions of numerous challenges involved in applying magnetic nanoparticles to cancer treatment.

Autorentext

Dr. Raghvendra A. Bohara, Ph.D., is currently working as an Irish Research Council Postdoctoral Fellow at CÚRAM, the Centre for Research in Medical Devices, Government of Ireland. He is also an Assistant Professor at the Centre for Interdisciplinary Research, D. Y. Patil Education Society, Kolhapur, India. His major reseach interests include magnetic triggered drug delivery and cancer nanomedicine.

He is a recipient of various prestigious fellowships, e.g. from the Government of India, Government of Ireland IRC Fellowship (2017), SERB Travel Grant Young Scientist Awardee, and an Excellence in Research Award for the year 2016-2017 awarded by the D. Y. Patil Education Society. Recently he was selected as an Associate Member of the Royal Society of Chemistry (UK).

Dr. Bohara has published more than 35 peer-reviewed journal articles, 4 book chapters and 1 book, is an Associate Editor for the journal Biochemistry and Biophysics Reports, and has served as a guest editor and reviewer for many other journals. He is also actively involved in teaching courses on stem cells, regenerative medicine and medical biotechnology for undergraduates and graduates.

Inhalt

Chapter 1. Magnetism in reduced dimension: Role in biomedical applications.- Chapter 2. Cancer: concept and newer therapies.- Chapter 3. Magnetic nanoparticles for cancer: the best approach from raw material to product development.- Chapter 4. Apoptosis cancer therapy tuning the magnetic nanoparticles.- Chapter 5. Magnetic triggered drug release: a newer paradigm in cancer therapy.- Chapter 6. Safeguarding the magnetic nanoparticles for enhancing the biocompatibility, half-life and biodegradability.- Chapter 7. Deliver, induce and trigger apoptosis: three arm approach to battle against cancer.- Chapter 8. Current challenges in translating magnetic nanoparticles in cancer therapy: pros and cons.