This volume summarizes the state-of-the-art technologies, key advances and future trends in the field of label-free biosensing. It provides detailed insights into the different types of solid-state, label-free biosensors, their underlying transducer principles, advanced materials utilized, device-fabrication techniques and various applications. The book offers graduate students, academic researchers, and industry professionals a comprehensive source of information on all facets of label-free biosensing and the future trends in this flourishing field.Highlights of the subjects covered include label-free biosensing with:

· semiconductor field-effect devices such as nanomaterial-modified capacitive electrolyte-insulator-semiconductor structures, silicon nanowire transistors, III-nitride semiconductor devices and light-addressable potentiometric sensors

· impedimetric biosensors using planar and 3D electrodes

· nanocavity and solid-state nanopore devices

· carbon nanotube and graphene/graphene oxide biosensors

· electrochemical biosensors using molecularly imprinted polymers

· biomimetic sensors based on acoustic signal transduction

· enzyme logic systems and digital biosensors based on the biocomputing concept

· heat-transfer as a novel transducer principle

· ultrasensitive surface plasmon resonance biosensors

· magnetic biosensors and magnetic imaging devices

Autorentext

Michael J. Schöning

Aachen University of Applied Sciences

Institute of Nano- and Biotechnologies

Heinrich-Mußmann-Str. 1

52428 Jülich, Germany

e-mail: schoening@fh-aachen.de

Arshak Poghossian

Aachen University of Applied Sciences

Institute of Nano- and Biotechnologies

Heinrich-Mußmann-Str. 1

52428 Jülich, Germany

e-mail: a.poghossian@fz-juelich.de

Inhalt

Nanomaterial-modified Capacitive Field-effect Biosensors.- Silicon Nanowire Field-effect Biosensors.- Label-free Biosensors Based on III-Nitride Semiconductors.- (Bio-)chemical Sensing and Imaging by LAPS and SPIM.- Biosensorial Application of Impedance Spectroscopy with Focus on DNA Detection.- Label-free Impedimetric Biosensing Using 3D Interdigitated Electrodes.- Electrochemical Nanocavity Devices.- Computational Modeling of Biomolecule Sensing with a Solid-state Membrane.- Amperometric Sensors Based on Carbon Nanotubes in Layer-by-Layer Films.- Graphene-based Biosensors and their Applications in Biomedical and Environmental Monitoring.- Label-free MIP-Sensors for Protein Biomarkers.- Biomimetic Recognition for Acoustic Sensing in Liquids.- Enzyme Logic Systems - Biomedical and Forensic Biosensor Applications.- Heat Transfer as a New Sensing Technique for the Label-Fee Detection of Biomolecules.- Towards Ultrasensitive Surface Plasmon Resonance Sensors.- Biomagnetic Sensing.