Within the last decade there have been a number of new and important areas of emphasis in HIV care and research, particularly in the context of brain involvement. Without question, clinical and research innovations in the modern era of the HIV pandemic warrant an update on HIV and the brain. Written by a panel of leading experts, HIV and the Brain: New Challenges in the Modern Era offers a clear picture of brain impairment associated with the virus with particular focus on three emerging areas including different genetic strains of the virus throughout the world, interactions between advanced age and HIV, and the impact of HIV on the brain in the context of chronic, long-term treatment with highly active antiretroviral therapy (HAART). HIV and the Brain: New Challenges in the Modern Era provides a comprehensive review of both basic science and clinical implications in these important areas of the disease. The text is of particular relevance to both research scientists and clinicians involved in HIV in the modern era.

Zusammenfassung

Written by leading experts, this book offers a picture of how HIV impairs the brain, focusing on emerging areas including genetic strains of the virus, interactions between advanced age and HIV, and the impact of HIV on the brain during antiretroviral therapy.

Inhalt
Neurocognitive Changes in AIDS: Evolution of Treatment of HIV Infection.- Global Incidence and Epidemiology of the AIDS Pandemic, Distribution of HIV Subtypes, and Epidemiology of Hepatitis C Infection Among HIV-Positive Individuals.- New Insights into HIV Neuropathogenesis.- Neuropathological Findings Associated with Long-Term HAART.- Biomarkers of HIV-Related Central Nervous System Disease.- Neuroimaging Among HIV-Infected Patients: Current Knowledge and Future Directions.- The Assessment of HIV-Associated Neurocognitive Disorders: New Challenges in the HAART Era.- The Changing Face of HIV-Associated Cognitive and Neuropsychiatric Disturbance.- Youth with HIV/AIDS: Neurobehavioral Consequences.- Co-Occurrence of HIV, Hepatitis C, and Substance Use Disorders: Effects on Brain Functioning.- The Functional Impact of HIV-Associated Neuropsychological Decline.- Adjunctive Therapy for Long-Term Support of Cognitive Impairment.- HIV-1 Genetic Diversity and Its Biological Significance.- Opportunistic Infections in the Brain in Developing Countries.- Impact of Clade Diversity on Neuropsychological Outcomes.- The Effects of Aging on HIV Disease.- Neuropsychology of Healthy Aging.- Interactions Between Advanced Age and HIV Cognitive Impairment.