This book is a comprehensive guide to Targeted Drug Delivery (TDD), also known as Intrathecal Drug Delivery (IDD), and offers an overview to this unique form of treatment. The medication is delivered by intrathecal pumps and is less common than some other techniques for interventional pain management, but is essential in conditions such as refractory pain, cancer pain, multifocal pain, severe spasticity, and in patients who are not candidates for surgical correction of their underlying condition.

This book is the first source to describe both the optimal surgical implantation and patient management aspect of this therapy, and thus will be a valuable single reference guide for interventional radiologists, anesthesiologists, physiatrists, oncologists, neurologists, spine surgeons, palliative care physicians, and primary care physicians.

Autorentext

Douglas P. Beall, MD, attended medical school at Georgetown University School of Medicine in Washington, DC, and completed his residency at The Johns Hopkins Hospital in Baltimore, Maryland. Following residency, he was Chief of Interventional Services at Sheppard Air Force Base in Wichita Falls, Texas. He then completed a fellowship in Musculoskeletal Radiology at Mayo Clinic in Rochester, Minnesota, where he was trained in interventional spine techniques before returning to the US Air Force as Division Chief of Musculoskeletal Radiology. Following his service as a Major in the US Air Force Dr. Beall was chief of Musculoskeletal Radiology and Fellowship Director at the Univiersity of Oklahoma prior to entering private practice as the Chief of Services.

In addition to his expertise in musculoskeletal imaging and interventional spine care, Dr. Beall is actively involved in teaching and research. He is board-certified in Diagnostic Radiology, has an added fellowship in Musculoskeletal Radiology, is a Diplomate of the American Academy of Pain Management and is a Fellow of the Society of Interventional Radiology and Interventional Pain Practice and board certified by the World Institute of Pain. He is currently in private practice focused on interventional pain management and orthopedic imaging. Dr. Beall has published more than 250 articles in peer-reviewed journals, authored 6 textbooks and 75 textbook chapters, given more than 1000 invited lectures and scientific presentations and has participated in 55 clinical research trials. He is currently the Chief of Services for Comprehensive Specialty Care in Oklahoma City as well as the Division Head of Interventional Spine Care and Director of Pain Management Fellowship Programs at the Center for Comprehensive Specialty Care.

Peter L Munk, MDCM, FRCPC, FSIR, FFRRCSI (Hon) is Professor of Radiology, Orthopedics and Palliative Care at the University of British Columbia and former Section Head Musculoskeletal Imaging at the Vancouver General Hospital in Vancouver, Canada. A medical graduate of McGill University in Montreal, Canada. Completed a Fellowship in musculoskeletal radiology at the University of California San Francisco. Previous Editor in Chief of the Canadian Association of Radiologists Journal (2009-2019) and currently Associate Editor of the British Journal of Radiology, Advisor to the Editor Medical Journal of Australia. International Liaison for the Asian Pacific Association of Medical Journal Editors. Author of 460 published papers, 180 abstracts, 120 scientific exhibits, 5 books and 25 book chapters. Member of the International Skeletal Society, Fellow of the Society of Interventional Radiology and Honorary Fellow of the Faculty of Radiology of the Royal College of Surgeons in Ireland.

Principle research interest includes musculoskeletal tumor imaging and Interventional imaging guided musculoskeletal procedures - particularly with regards to pain control in metastatic bone disease.

Michael J. DePalma, MD is President and Medical Director of Virginia iSpine Physicians, PC where he practices Interventional Spine and Musculoskeletal Care. Dr. DePalma completed his residency in Physical Medicine and Rehabilitation at The Ohio State University Medical Center in 2003 followed by his fellowship training in Interventional Spine Care at the Pennsylvania Spine Center of the Hospital of the University of Pennsylvania in 2004.

Dr. DePalma has authored or co-authored over eighty-five articles and abstracts in peer reviewed journals and twenty-one textbook chapters. He has also edited a forty-nine chapter textbook, iSpine: Evidence Based Interventional Spine Care, and co-edited a second textbook, Regenerative Medicine: The Intersection of Research and Experience. He serves or has served on multiple professional committees and boards for the North American Spine Society, The Spine Intervention Society, and the American Academy of Physical Medicine and Rehabilitation. Dr. DePalma is a reviewer for leading peer reviewed journals within his specialty as well as online patient education website. He serves as Director of Virginia iSpine Physician's Interventional Spine Care Fellowship program and is also Chairman and Director of Research with Virginia Spine Research Institute. Dr. DePalma has been named by his peer physicians as a Top Doc in Richmond Magazine in 2008, 2011, and 2012, in Best Doctors in America 2015-2016, and in Virginia magazine in 2017. This esteemed recognition places Dr. DePalma within the top 10% of recognized physicians in this area. He is also the recipient of the 2018 Our Health Best Bedside Manner Award as well as the 2019 Medarva Patient Choice Award.

Dr. DePalma is an active spine and musculoskeletal researcher with over 1...

Inhalt
Introduction and Background for Intrathecal Pumps Used for Pain and Spasticity.- Intrathecal Drug Delivery for Cancer Related Pain.- The Components of Intrathecal Drug Delivery.- Intrathecal Drug Delivery Trialing.- Targeted Drug Delivery Perioperative Planning Considerations.- Key Steps in the Intrathecal Pain Pump Procedure.- Intrathecal Pump Management.- Pump Management.- Intrathecal Baclofen Pumps.- Post-Operative Care and Complication.- Intrathecal Pump and Catheter Troubleshooting.- Current Intrathecal Pump Costs, Coding and Reimbursement.- Interventional Pain Management in Palliative Care.- The Use of Ziconotide in Intrathecal Drug Therapy.