This book gathers the proceedings of the 17th International Conference on Intracranial Pressure and Neuromonitoring, held in Leuven, Belgium in September 2019. It provides an overview of the current understanding, underlying research and future perspectives concerning pathophysiology, biophysics, monitoring and management in traumatic and non-traumatic acute brain injury, hydrocephalus and spinal cord injury, including cerebrovascular autoregulation impairment in neurological as well as non-neurological diseases. The peer-reviewed contributions were prepared by specialists in neurosurgery, neurointensive care and neuroanesthesiology, as well as prominent experts from the fields of physiology, clinical and biomedical engineering, mathematics and informatics. The book continues the time-honored tradition of publishing key presentations from the ICP Conferences in order to facilitate their dissemination within the clinical and research community.

Autorentext

Dr. Bart Depreitere graduated at the Medical School of the KULeuven (Belgium) in 1997. He completed his neurosurgical training in Leuven and was board-certified in 2004. Also in 2004, he received his PhD in Medical Sciences at KULeuven by defending a doctoral thesis 'A rational approach toward pedal cyclist head protection'. He did a fellowship in neurosurgery at the University of Toronto in 2005-2006. Since 2006, he works as a staff neurosurgeon at the University Hospitals Leuven. He is appointed professor at the KULeuven and teaches spine pathology for physiotherapy students and neurosurgery for medical students. His research is in physiology and biomechanics of traumatic brain injury combining both clinical data, animal models and mathematical models and he authored several publications in this field.

Professor Geert Meyfroidt graduated as a MD in 1996, has a board certification in anesthesiology (2001) and intensive care medicine (2004), is clinically active as Senior Consultant at the Department of Intensive Care Medicine of the University Hospitals Leuven, and has an academic appointment as Associate Professor of Medicine at the University of Leuven (KU Leuven), Belgium. In 2010, he finished his PhD, entitled, Computerized data management in the intensive care unit: predictive modeling, time series analysis, and opportunities for support of care. He is funded by the Flemish Government (Research Foundation Flanders (FWO)), as Senior Clinical Researcher (2012-2017: 1843113N and 2017-2022: 1843118N) and has project funding from the KU Leuven (KU Leuven C2 project (C24/17/072): A Neuromonitor for the 21st century). Current research projects include: data mining and predictive modeling in neuro-intensive care and acute kidney injury; cerebrovascular autoregulation; brain Injury and ketamine. He is promotor and co-promotor of 5 PhD students, has authored and co-authored more than 80 medical journal articles, and is a regular speaker at national and international conferences. As of 2019, he serves as Associate Editor in the editorial board of Intensive Care Medicine. Professor Meyfroidt was elected country representative for Belgium at the European Society of Intensive Care Medicine (ESICM)(2012-2015), is now the chair of the Neuro-Intensive Care section of ESICM (2019-2022), and the Scientific Panel of the European Academy of Neurology. He is the current president of the Belgian Society of Intensive Care Medicine (SIZ) (2019-2021). In 2016, he received the Established Investigator Award from the ESICM (20K ).

Inhalt
PART I ~ NEUROMONITORING AND MANAGEMENT IN ADULT TRAUMATIC BRAIN INJURY 1 ~ 1129 Microcirculatory Biomarkers of Secondary Cerebral Ischemia at Traumatic Brain Injury.- 2 ~ 1165 Visualisation of ICP Insults After Severe TBI; Influence of Individualised Limits of Reactivity.- 3 ~ 1178 Pressure Challenge Impact on Cerebral Critical Closing Pressure and Effective CPP in Traumatic Brain Injury Patients.- 4 ~ 1204 Semi-automated CT Volumetry as Proxy for Intracranial Pressure in Patients with Severe Traumatic Brain Injury: Clinical Feasibility Study.- 5 ~ 1224 The Error and Consequences of Inaccurate Estimation of Mean Blood Flow Velocity in Cerebral Arteries.- 6 ~ 1235 Analysis of Association Between Lung Function and Brain Tissue Oxygen Tension in Severe Traumatic Brain Injury.- 7 ~ 1246 A Comparison of Two ICP Calculation Methods and Their Effects on Mean-ICP and ICP Dose.- 8 ~ 1263 External Hydrocephalus After Traumatic Brain Injury: Retrospective Study of 102 Patients.- 9 ~ 1288 Analyzing Cardio-Cerebral Crosstalks in an Adult Cohort from CENTER-TBI.- 10 ~ 1308 Cerebrovascular Consequences of Elevated Intracranial Pressure After Traumatic Brain Injury.- PART II ~ NEUROMONITORING AND MANAGEMENT IN ADULT NON-TRAUMATIC BRAIN INJURY 11 ~ 1130 The Assessment of Cerebral Autoregulation in the Perifocal Zone of a Chronic Subdural Hematoma.- 12 ~ 1210 Noninvasive Intracranial Pressure Monitoring in Chronic Stroke Patients with Sedentary Behavior - Pilot Study.- 13 ~ 1291 Investigating Changes in Intracranial Pressure Waveform Morphology in Patients with Ventriculitis Using Clustering.- 14 ~ 1292 Perioperative Dynamics of Intracranial B-waves of Blood Flow Velocity in Basal Cerebral Arteries in Patients with Brain Arteriovenous Malformation.- PART III ~ NEUROMONITORING AND MANAGEMENT IN ADULT MIXED BRAIN INJURY POPULATIONS 15 ~ 1139 The Effect of Hyperthermia on the Intracranial Pressure and Cerebral Autoregulation in Patients with Acute Brain Injury.- 16 ~ 1194 A Comparative Study on the Effect of Early Versus Late Cranioplasty in Cognitive Function.- 17 ~ 1195 Effect of Cranioplasty After Decompressive Craniectomy in Traumatic Versus Non Traumatic Brain Injury on Neurological Function and Cerebral Hemodynamics.- 18 ~ 1221 Brain Multimodal Monitoring in Severe Acute Brain Injury: Is It Relevant for Outcome and Mortality?.- 19 ~ 1239 Long-term Outcome After Decompressive Craniectomy in a Developing Country.- 20 ~ 1357 Predictors of Successful Extubation in Neurocritical Patients.- PART IV ~ NEUROMONITORING AND MANAGEMENT IN THE PEDIATRIC POPULATION 21 ~ 1160 Impaired Autoregulation Following Resuscitation Correlates to Outcome in Pediatric Patients: A Pilot Study.- 22 ~ 1171 Brain Biomarkers in Children After Mild and Severe Brain Traumatic Injury.- 23 ~ 1200 Decompressive Craniectomy for Traumatic Intracranial Hypertension in Children.- 24 ~ 1214 The Use of Direct ICP and Brain Tissue Oxygen Monitoring in the Perioperative Management of Patients with Moyamoya Disease.- PART V ~ NEUROMONITORING TECHNOLOGY 25 ~ 1118 Optic Nerve Sheath Diameter Threshold for Increased Intracranial Pressure Are Not Related to Sex and Age in Traumatic Brain Injury.- 26 ~ 1120 A Noninvasive Method for Monitoring Intracranial Pressure During Postural Changes.- 27 ~ 1187 Arterial and Venous Cerebrovascular Flow Velocities Coupling in Healthy Volunteers and Traumatic Brain Injured Patients.- 28 ~ 1309 Comparison of Waveforms Between Non-invasive and Invasive ICP Monitoring.- PART VI ~ CEREBROVASCULAR AUTOREGULATION IN ACUTE BRAIN INJURY AND CARDIAC SURGERY 29 ~ 1169 An Update on the COGiTATE Phase II Study: Feasibility and Safety of Targeting an Optimal Cerebral Perfusion Pressure as a Patient-Tailored Therapy in Severe Traumatic Brain Injury.- 30 ~ 1223 Quick Assessment of the Low Limit of Autoregulation (LLA) with the Transcranial Doppler During Cardiac Surgery.- 31 ~ 1231 Influence of Patient Demographics on Optimal Cerebral Perfusion Pressure Following Traumatic Brain Injury.- 32 ~ 1261 Secondary Cerebral Ischemia at Traumatic Brain Injury is More Closely Related to Cerebrovascular Reactivity Impairment than to Intracranial Hypertension.- 33 ~ 1265 Usability of the Non-invasive Counterparts…